即时检测在呼吸道病毒感染中的应用。
Point-of-care diagnostics for respiratory viral infections.
机构信息
a Centre for Infectious Diseases and Microbiology Laboratory Services , Institute of Clinical Pathology and Medical Research, NSW Health Pathology , Westmead , Australia.
b Marie Bashir Institute for Emerging Infections and Biosecurity , University of Sydney, Westmead Hospital , Westmead , Australia.
出版信息
Expert Rev Mol Diagn. 2018 Jan;18(1):75-83. doi: 10.1080/14737159.2018.1419065. Epub 2017 Dec 26.
Abstract
Successful treatment outcomes for viral respiratory tract infections presenting from primary health care to quaternary hospitals will only be achieved with rapid, sensitive and specific identification of pathogens to allow effective pathogen-specific antiviral therapy and infection control measures. Areas covered: This review aims to explore the different point-of-care tests currently available to diagnose viral respiratory tract infections, discuss the advantages and limitations of point-of-care testing, and provide insights into the future of point-of-care tests. The following databases were searched: Medline (January 1996 to 30 September 2017) and Embase (1988 to 30 September 2017), using the following keywords: 'point of care', 'respiratory virus', 'influenza', 'RSV', 'diagnostics', 'nucleic acid test' and 'PCR'. Expert commentary: Viral respiratory tract infections cause significant morbidity and mortality worldwide, and point-of-care tests are facilitating the rapid identification of the pathogen responsible given the similarities in clinical presentation.
摘要
成功治疗源自初级保健到四级医院的病毒性呼吸道感染的结果，只有通过快速、敏感和特异性地识别病原体，才能实现有效的针对病原体的抗病毒治疗和感染控制措施。
涵盖领域
本综述旨在探讨目前可用于诊断病毒性呼吸道感染的不同即时检测方法，讨论即时检测的优缺点，并深入了解即时检测的未来。检索了以下数据库：Medline（1996 年 1 月至 2017 年 9 月 30 日）和 Embase（1988 年至 2017 年 9 月 30 日），使用以下关键词：“即时检测”、“呼吸道病毒”、“流感”、“RSV”、“诊断”、“核酸检测”和“PCR”。
专家评论
病毒性呼吸道感染在全球范围内造成了显著的发病率和死亡率，由于临床表现相似，即时检测有助于快速识别病原体。
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