1 Department of Otolaryngology, Gyeongsang National University , Jinju, Korea.
2 Department of Nursing Graduate School, Gyeongsang National University , Jinju, Korea.
Thyroid. 2018 Feb;28(2):236-245. doi: 10.1089/thy.2017.0277. Epub 2018 Jan 18.
The objective of this study was to determine the effect of a home-based exercise program on fatigue, anxiety, quality of life (QoL), and immune function of thyroid cancer patients taking thyroid hormone replacement after thyroidectomy.
This quasi-experimental study with a non-equivalent control group included 43 outpatients taking thyroid hormone replacement after thyroidectomy (22 in the experimental group and 21 in the control group). After education about the home-based exercise program, subjects in the experimental group underwent 12 weeks of aerobic, resistance, and flexibility exercise. A comparative analysis was conducted between the two groups.
Patients in the experimental group were significantly less fatigued or anxious (p < 0.01). They reported significantly improved QoL (p < 0.05) compared to those in the control group. Natural killer cell activity was significantly higher in the exercise group compared to that in the control group (p < 0.05).
A home-based exercise program is effective in reducing fatigue and anxiety, improving QoL, and increasing immune function in patients taking thyroid hormone replacement after thyroidectomy. Therefore, such a home-based exercise program can be used as an intervention for patients who are taking thyroid hormone replacement after thyroidectomy.
本研究旨在确定家庭运动方案对甲状腺癌患者在甲状腺切除术后服用甲状腺激素替代治疗后的疲劳、焦虑、生活质量（QoL）和免疫功能的影响。
这是一项具有非均等对照组的准实验研究，共纳入 43 名甲状腺切除术后服用甲状腺激素替代治疗的门诊患者（实验组 22 名，对照组 21 名）。在接受家庭运动方案教育后，实验组进行了 12 周的有氧运动、阻力运动和柔韧性运动。对两组进行了对比分析。
实验组患者的疲劳或焦虑程度明显较低（p<0.01）。与对照组相比，实验组患者的 QoL 显著改善（p<0.05）。与对照组相比，实验组患者的自然杀伤细胞活性明显更高（p<0.05）。
家庭运动方案可有效减轻甲状腺切除术后服用甲状腺激素替代治疗患者的疲劳和焦虑，改善 QoL，增强免疫功能。因此，这种家庭运动方案可作为甲状腺切除术后服用甲状腺激素替代治疗患者的干预措施。
