Ogawa Sumito, Yakabe Mitsutaka, Akishita Masahiro
Department of Geriatric Medicine, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo 113-8655 Japan.
Inflamm Regen. 2016 Sep 7;36:17. doi: 10.1186/s41232-016-0022-5. eCollection 2016.
Age-related loss of the skeletal muscle and its function is known as sarcopenia. Definition and diagnostic criteria for sarcopenia have been outlined as consensus statements from several study groups, including usual gait speed, grip strength, and skeletal muscle mass. Whereas underlying mechanisms and pathophysiology of sarcopenia remains to be clarified, recent studies have suggested that chronic inflammatory status as well as lifestyle-related factors in older individuals might contribute to the process and progress of sarcopenia.
与年龄相关的骨骼肌及其功能丧失被称为肌肉减少症。包括通常的步态速度、握力和骨骼肌质量在内的几个研究小组已将肌肉减少症的定义和诊断标准概述为共识声明。虽然肌肉减少症的潜在机制和病理生理学仍有待阐明，但最近的研究表明，老年人的慢性炎症状态以及与生活方式相关的因素可能会导致肌肉减少症的发生和发展。
