Emerg Infect Dis. 2018 Jan;24(1):1-8. doi: 10.3201/eid2401.170979.
Zika virus infection during pregnancy can lead to congenital Zika syndrome. Implementation of screening programs and interpretation of test results can be particularly challenging during ongoing local mosquitoborne transmission. We conducted a retrospective chart review of 2,327 pregnant women screened for Zika virus in Miami-Dade County, Florida, USA, during 2016. Of these, 86 had laboratory evidence of Zika virus infection; we describe 2 infants with probable congenital Zika syndrome. Delays in receipt of laboratory test results (median 42 days) occurred during the first month of local transmission. Odds of screening positive for Zika virus were higher for women without health insurance or who did not speak English. Our findings indicate the increase in screening for Zika virus can overwhelm hospital and public health systems, resulting in delayed receipt of results of screening and confirmatory tests and the potential to miss cases or delay diagnoses.
孕妇感染 Zika 病毒可导致先天性 Zika 综合征。在蚊媒传播仍在持续的地区，实施筛查项目和解释检测结果可能极具挑战性。我们对美国佛罗里达州迈阿密-戴德县 2016 年筛查 Zika 病毒的 2327 名孕妇进行了回顾性病历审查。其中 86 例实验室证据表明 Zika 病毒感染；我们描述了 2 例可能患有先天性 Zika 综合征的婴儿。在当地传播的第一个月，实验室检测结果的送达时间（中位数为 42 天）延迟。没有医疗保险或不会说英语的妇女筛查 Zika 病毒呈阳性的几率更高。我们的研究结果表明，Zika 病毒筛查的增加可能使医院和公共卫生系统不堪重负，导致筛查和确认检测结果的送达时间延迟，并有可能漏诊病例或延误诊断。
