Rode Anuja, Sharma Sanjay, Mishra Dinesh K
NMIMS, School of Pharmacy and Technology Management, Shirpur, District Dhule, Maharastra, 425405, India.
Curr Drug Deliv. 2018;15(5):620-629. doi: 10.2174/1567201815666171221124711.
Nanoscience and nanotechnology are emerging areas in the pharmaceutical sciences and the need of modernizing world. Nanoscience is the world of atoms, macromolecular assemblies, macromolecules, quantum dots, and molecules. Nanoscience is the study, and understanding control of phenomena and manipulation of material at the nanoscale. Carbon nanotubes are a tube like material mainly made up of carbon. Only carbon nanotubes are the macromolecules of graphite consisting of sheets of carbon, which is weaved into the cylinder. Graphite sheets look like a hexagonal in shape Nano carbon tubes are about 2 millimetres long and these are one hundred times as stiff as steel. The arrangement of atom in a carbon nanotube is in a form of hexagonal as like as graphite. Carrying capacity of carbon nanotube is 1000 times higher than that of copper thermal stability of it is 4000k, it can be semiconducting or metallic, depending on their diameter and chirality of the atom. These carbon nanotubes having various classifications like single walled CNT's, Multiwalled CNT's, Nano horns, Nano buds, polymerized single walled nanotubes. The review is more focused towards the methods of preparation of nanotubes and their general various applications in pharmacy and medicine along with toxicity. These carbon Nano tubes can be prepared by using various methods with successful ease or application in pharmaceuticals, i.e. gas storage, adsorption, catalyst supported, delivery of drug through targeted system, electrochemistry, bio sensing, fuel cell, photodynamic cells, etc. CNT's are advanced technology in the era of nanotechnology in pharmaceutical sciences which are more emphasizing on patient's compliance and safety. Possessing a broad area of application along with targeted drug delivery. The Scientists are still exploring the various applications of it.
纳米科学和纳米技术是制药科学以及现代世界发展需求中新兴的领域。纳米科学涵盖原子、大分子聚集体、大分子、量子点和分子的世界。纳米科学是对纳米尺度现象的研究、理解、控制以及对材料的操纵。碳纳米管是一种主要由碳构成的管状材料。只有碳纳米管是由碳片编织成圆柱体的石墨大分子。石墨片呈六边形，纳米碳管长度约为2毫米，其硬度是钢的100倍。碳纳米管中原子的排列形式与石墨一样呈六边形。碳纳米管的承载能力比铜高1000倍，其热稳定性为4000K，根据其直径和原子手性，它可以是半导体或金属。这些碳纳米管有多种分类，如单壁碳纳米管、多壁碳纳米管、纳米角、纳米芽、聚合单壁纳米管。本综述更侧重于纳米管的制备方法及其在制药和医学中的一般各种应用以及毒性。这些碳纳米管可以通过各种方法轻松制备并成功应用于制药领域，如气体储存、吸附、负载催化剂、通过靶向系统给药、电化学、生物传感、燃料电池、光动力电池等。碳纳米管是制药科学纳米技术时代的先进技术，更强调患者的依从性和安全性。它具有广泛的应用领域以及靶向给药功能。科学家们仍在探索其各种应用。
