Department of Medicine, Duke University Medical Center, Durham, North Carolina.
Geriatric Research, Education, and Clinical Center, Durham Veterans Affairs Medical Center, Durham, North Carolina.
JAMA Surg. 2018 May 1;153(5):454-462. doi: 10.1001/jamasurg.2017.5513.
Older adults undergoing elective surgery experience higher rates of preventable postoperative complications than younger patients.
To assess clinical outcomes for older adults undergoing elective abdominal surgery via a collaborative intervention by surgery, geriatrics, and anesthesia focused on perioperative health optimization.
DESIGN, SETTING, AND PARTICIPANTS: Perioperative Optimization of Senior Health (POSH) is a quality improvement initiative with prospective data collection. Participants in an existing geriatrics-based clinic within a single-site academic health center were included if they were at high risk for complications (ie, older than 85 years or older than 65 years with cognitive impairment, recent weight loss, multimorbidity, or polypharmacy) undergoing elective abdominal surgery. Outcomes were compared with a control group of patients older than 65 years who underwent similar surgeries by the same group of general surgeons immediately before implementation of POSH.
Primary outcomes included length of stay, 7- and 30-day readmissions, and level of care at discharge. Secondary outcomes were delirium and other major postoperative complications. Outcomes data were derived from institutional databases linked with electronic health records and billing data sets.
One hundred eighty-three POSH patients were compared with 143 patients in the control group. On average, patients in the POSH group were older compared with those in the control group (75.6 vs 71.9 years; P < .001; 95% CI, 2.27 to 5.19) and had more chronic conditions (10.6 vs 8.5; P = .001; 95% CI, 0.86 to 3.35). Median length of stay was shorter among POSH patients (4 days vs 6 days; P < .001; 95% CI, -1.06 to -4.21). Patients in the POSH group had lower readmission rates at 7 days (5 of 180 [2.8%] vs 14 of 142 [9.9%]; P = .007; 95% CI, 0.09 to 0.74) and 30 days (14 of 180 [7.8%] vs 26 of 142 [18.3%]; P = .004; 95% CI, 0.19 to 0.75) and were more likely to be discharged home with self-care (114 of 183 [62.3%] vs 73 of 143 [51.1%]; P = .04; 95% CI, 1.02 to 2.47). Patients in the POSH group experienced fewer mean number of complications (0.9 vs 1.4; P < .001; 95% CI, -0.13 to -0.89) despite higher rates of documented delirium (52 of 183 [28.4%] vs 8 of 143 [5.6%]; P < .001; 95% CI, 3.06 to 14.65). A greater proportion of POSH patients underwent laparoscopic procedures (92 of 183 [50%] vs 55 of 143 [38.5%]; P = .001; 95% CI, 1.04 to 2.52). Tests for interactions between POSH patients and procedure type were insignificant for all outcomes.
Despite higher mean age and morbidity burden, older adults who participated in an interdisciplinary perioperative care intervention had fewer complications, shorter hospitalizations, more frequent discharge to home, and fewer readmissions than a comparison group.
接受择期手术的老年患者比年轻患者更容易发生可预防的术后并发症。
通过外科、老年医学和麻醉科共同关注围手术期健康优化的协作干预措施,评估老年患者接受择期腹部手术的临床结果。
设计、地点和参与者:围手术期优化老年健康(POSH)是一项具有前瞻性数据收集的质量改进计划。如果患者有发生并发症的高风险(即年龄大于 85 岁或年龄大于 65 岁且认知障碍、近期体重减轻、多种疾病或多种药物治疗),正在接受择期腹部手术,则将他们纳入单站点学术医疗中心内现有的基于老年医学的诊所。将与 POSH 实施前由同一组普通外科医生为接受类似手术的年龄大于 65 岁的患者进行的对照研究进行比较。
主要结果包括住院时间、7 天和 30 天再入院率以及出院时的护理水平。次要结果是谵妄和其他主要术后并发症。结果数据来自与电子健康记录和计费数据集相关联的机构数据库。
将 183 名 POSH 患者与对照组的 143 名患者进行了比较。平均而言,POSH 组患者比对照组患者年龄更大(75.6 岁比 71.9 岁;P<0.001;95%CI,2.27 至 5.19),并且患有更多的慢性疾病(10.6 比 8.5;P=0.001;95%CI,0.86 至 3.35)。POSH 患者的中位住院时间更短(4 天比 6 天;P<0.001;95%CI,-1.06 至 -4.21)。POSH 组患者在 7 天(5/180[2.8%]比 14/142[9.9%];P=0.007;95%CI,0.09 至 0.74)和 30 天(14/180[7.8%]比 26/142[18.3%];P=0.004;95%CI,0.19 至 0.75)的再入院率较低,并且更有可能在出院时能够自理(114/183[62.3%]比 73/143[51.1%];P=0.04;95%CI,1.02 至 2.47)。尽管 POSH 组患者发生谵妄的记录率较高(52/183[28.4%]比 8/143[5.6%];P<0.001;95%CI,3.06 至 14.65),但 POSH 组患者的平均并发症数量更少(0.9 比 1.4;P<0.001;95%CI,-0.13 至 -0.89)。POSH 组患者中接受腹腔镜手术的比例更高(92/183[50%]比 55/143[38.5%];P=0.001;95%CI,1.04 至 2.52)。对于所有结果,POSH 患者和手术类型之间的交互作用检验均不显著。
尽管平均年龄和发病负担较高,但参与跨学科围手术期护理干预的老年患者与对照组相比,并发症更少,住院时间更短,出院回家的频率更高,再入院率更低。