Sutin Angelina R, Stephan Yannick, Terracciano Antonio
Florida State University College of Medicine, Tallahassee, FL, USA.
Euromov, University of Montpellier, Montpellier, France.
Int J Geriatr Psychiatry. 2018 May;33(5):743-747. doi: 10.1002/gps.4849. Epub 2018 Jan 3.
Well-being is a psychological resource that buffers against age-related disease. We test whether this protective effect extends to dementia and whether it is independent of distress.
Participants (N = 10,099) were from the Health and Retirement Study. Five aspects of positive psychological functioning (life satisfaction, optimism, mastery, purpose in life, and positive affect) were tested as predictors of incident dementia over 6 to 8 years.
Purpose in life was associated with a 30% decreased risk of dementia, independent of psychological distress, other clinical and behavioral risk factors, income/wealth, and genetic risk. After controlling for distress and other risk factors, the other aspects of well-being were not associated with dementia risk.
After considering psychological distress, we found that measures of well-being were generally not protective against risk of dementia. An exception is purpose in life, which suggests that a meaningful and goal-driven life reduces risk of dementia.
幸福感是一种心理资源，可缓冲与年龄相关的疾病。我们测试这种保护作用是否扩展到痴呆症，以及它是否独立于痛苦情绪。
参与者（N = 10,099）来自健康与退休研究。测试了积极心理功能的五个方面（生活满意度、乐观主义、掌控感、生活目的和积极情绪）作为6至8年内痴呆症发病的预测因素。
生活目的与痴呆症风险降低30%相关，独立于心理痛苦、其他临床和行为风险因素、收入/财富以及遗传风险。在控制了痛苦情绪和其他风险因素后，幸福感的其他方面与痴呆症风险无关。
在考虑心理痛苦后，我们发现幸福感指标通常对痴呆症风险没有保护作用。生活目的是个例外，这表明有意义且目标驱动的生活可降低痴呆症风险。
