短期致癌物暴露后，冷冻手术对仓鼠颊囊无肿瘤促进作用。
Lack of tumour potentiating effect of cryosurgery in hamster cheek pouch after short term carcinogen exposure.
作者信息
MacDonald D G, Critchlow H A
出版信息
Br J Oral Maxillofac Surg. 1985 Oct;23(5):341-5. doi: 10.1016/0266-4356(85)90005-1.
PMID:2932146
Abstract
Hamster cheek pouch was treated with the topical carcinogen DMBA for 2, 4 or 6 weeks. Cryosurgery to part of the treated area did not produce any alteration in subsequent tumour development. This contrasted with previous studies where cryosurgery following 8 weeks of DMBA application potentiated subsequent tumour development.
摘要
用局部致癌物二甲基苯并蒽（DMBA）处理仓鼠颊囊2、4或6周。对部分处理区域进行冷冻手术并未对后续肿瘤发展产生任何改变。这与之前的研究形成对比，在之前的研究中，应用DMBA 8周后进行冷冻手术会促进后续肿瘤发展。
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