Eveson J W, MacDonald D G
Br J Dermatol. 1978 Jun;98(6):639-44. doi: 10.1111/j.1365-2133.1978.tb03582.x.
Sequential changes in the hamster cheek pouch epithelium following application of the carcinogen dimethyl benzanthracene have been assessed using stereological techniques. The most important progressive change found following cessation of carginogen painting appears to be an increase in the number and size of progenitor cells. Much of the marked increase in stratum corneum thickness seen in the early stages appeared to be related to a hyperplasiogenic rather than a neoplasiogenic action of the carcinogen.
使用体视学技术评估了致癌物质二甲基苯并蒽应用后仓鼠颊囊上皮的连续变化。在停止涂抹致癌物质后发现的最重要的渐进性变化似乎是祖细胞数量和大小的增加。在早期观察到的角质层厚度的显著增加，很大程度上似乎与致癌物的增生性作用而非致瘤性作用有关。
