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本文引用的文献

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Neisseria gonorrhoeae Antimicrobial Susceptibility Surveillance - The Gonococcal Isolate Surveillance Project, 27 Sites, United States, 2014.淋病奈瑟菌抗菌药物敏感性监测 - 淋球菌分离株监测项目，美国 27 个监测点，2014 年。
MMWR Surveill Summ. 2016 Jul 15;65(7):1-19. doi: 10.15585/mmwr.ss6507a1.
2
Comparison of antimicrobial susceptibilities of pharyngeal, rectal, and urethral Neisseria gonorrhoeae isolates among men who have sex with men.男男性行为者中咽部、直肠和尿道淋病奈瑟菌分离株的抗菌药物敏感性比较。
Antimicrob Agents Chemother. 2015 May;59(5):2588-95. doi: 10.1128/AAC.04476-14. Epub 2015 Feb 17.
3
The efficacy and safety of gentamicin plus azithromycin and gemifloxacin plus azithromycin as treatment of uncomplicated gonorrhea.庆大霉素联合阿奇霉素以及吉米沙星联合阿奇霉素治疗单纯性淋病的疗效与安全性。
Clin Infect Dis. 2014 Oct 15;59(8):1083-91. doi: 10.1093/cid/ciu521. Epub 2014 Jul 16.
4
Cephalosporin and azithromycin susceptibility in Neisseria gonorrhoeae isolates by site of infection, British Columbia, 2006 to 2011.2006 年至 2011 年不列颠哥伦比亚省不同感染部位淋病奈瑟菌分离株头孢菌素和阿奇霉素药敏性。
Sex Transm Dis. 2013 Jan;40(1):46-51. doi: 10.1097/OLQ.0b013e31827bd64c.
5
Cephalosporin resistant Neisseria gonorrhoeae: time to consider gentamicin?耐头孢菌素淋病奈瑟菌：是时候考虑庆大霉素了？
Sex Transm Infect. 2012 Feb;88(1):6-8. doi: 10.1136/sextrans-2011-050362.
6
An evaluation of gentamicin susceptibility of Neisseria gonorrhoeae isolates in Europe.欧洲淋病奈瑟菌分离株的庆大霉素敏感性评价。
J Antimicrob Chemother. 2011 Mar;66(3):592-5. doi: 10.1093/jac/dkq476. Epub 2010 Dec 14.
7
Neisseria gonorrhoeae antimicrobial susceptibility in Lilongwe, Malawi, 2007.2007 年马拉维利隆圭淋病奈瑟菌的药敏性。
Sex Transm Dis. 2010 Mar;37(3):169-72. doi: 10.1097/OLQ.0b013e3181bf575c.
8
The use of cephalosporins for gonorrhea: the impending problem of resistance.头孢菌素用于淋病治疗：迫在眉睫的耐药性问题。
Expert Opin Pharmacother. 2009 Mar;10(4):555-77. doi: 10.1517/14656560902731993.
9
Emerging antimicrobial resistance in Neisseria gonorrhoeae: urgent need to strengthen prevention strategies.淋病奈瑟菌新出现的抗菌药物耐药性：迫切需要加强预防策略。
Ann Intern Med. 2008 Apr 15;148(8):606-13. doi: 10.7326/0003-4819-148-8-200804150-00005.
10
Cephalosporin allergy.头孢菌素过敏。
N Engl J Med. 2001 Sep 13;345(11):804-9. doi: 10.1056/NEJMra993637.

淋病奈瑟菌对庆大霉素的敏感性-淋病分离株监测项目，2015-2016 年。

Susceptibility of Neisseria gonorrhoeae to Gentamicin-Gonococcal Isolate Surveillance Project, 2015-2016.

机构信息

From the Division of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA.

出版信息

Sex Transm Dis. 2018 Feb;45(2):96-98. doi: 10.1097/OLQ.0000000000000693.

DOI:10.1097/OLQ.0000000000000693
PMID:29324629
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5861718/
Abstract

The gentamicin minimum inhibitory concentrations (MICs) of Neisseria gonorrhoeae isolates were determined. Seventy-three percent of isolates demonstrated an MIC range of 8 to 16 μg/mL, and 27% demonstrated an MIC of 4 μg/mL or less. Significant associations between gentamicin MIC and resistance or reduced susceptibility to other antimicrobials were found.

摘要

对淋病奈瑟菌分离株的庆大霉素最小抑菌浓度（MIC）进行了测定。73%的分离株的 MIC 范围为 8 至 16μg/ml，27%的分离株的 MIC 为 4μg/ml 或更低。发现庆大霉素 MIC 与其他抗菌药物的耐药性或降低敏感性之间存在显著关联。