Roy A, Breier A, Doran A R, Pickar D
J Affect Disord. 1985 Sep;9(2):143-8. doi: 10.1016/0165-0327(85)90093-x.
Life events that had occurred in the 6 months before the onset of depression were recorded in 40 depressed patients and 41 normal controls. The depressed patients had experienced significantly more life events and significantly more undesirable life events than the controls. The 20 patients with a DSM-III diagnosed major depressive episode (MDE) without melancholia had experienced significantly more life events in the 6 months before the onset of depression than the 20 patients with a major depressive episode with melancholia. The patients with MDE without melancholia, but not the MDE with melancholia patients, had also experienced significantly more life events than a group of age- and sex-matched normal controls.
研究记录了40名抑郁症患者和41名正常对照者在抑郁症发作前6个月内发生的生活事件。与对照组相比，抑郁症患者经历的生活事件显著更多，不良生活事件也显著更多。20名被诊断为无抑郁特征的重度抑郁发作（MDE）的患者在抑郁症发作前6个月内经历的生活事件比20名有抑郁特征的重度抑郁发作患者显著更多。无抑郁特征的MDE患者，而非有抑郁特征的MDE患者，与一组年龄和性别匹配的正常对照者相比，经历的生活事件也显著更多。
