Nutrition and Dietetics Group, School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Sydney, NSW 2006, Australia.
Faculty of Health Science, Discipline of Exercise and Sports Science, The University of Sydney, Lidcombe, NSW 2414, Australia.
Nutrients. 2018 Jan 12;10(1):81. doi: 10.3390/nu10010081.
Iron is an essential micronutrient for human health and inadequate intake may result in iron deficiency (ID) or iron deficiency anaemia (IDA). Unlike other recent studies investigating iron status in young women, this cross-sectional study analysed dietary intake and biochemical data from healthy young (18-35 years) women ( = 299) to determine the association between both haem iron (HI) and non-haem iron (NHI) intakes and serum ferritin (SF). Dietary restraint and possible inflammation secondary to obesity were also measured and accounted for, and energy intake was adjusted for using the residuals method. Independent samples -tests and chi-squared tests were performed, and factors found to be significantly different between iron replete (IR) and ID/IDA participants were analysed using general linear modelling. ID/IDA participants consumed significantly lower total energy than iron replete (IR) ( = 0.003). Lower energy intake was also associated with higher levels of dietary restraint ( = 0.001). Both HI and NHI were positively associated with SF with HI was found to be a stronger predictor ( = 0.128, = 0.009) than NHI ( = 0.037, = 0.028). The study demonstrates that intake of both HI and NHI, as well as adequate dietary energy, are associated with normal iron status levels in young women, and that restrained eaters may be at greater risk of low iron status.
铁是人体健康所必需的微量元素,摄入不足可能导致缺铁(ID)或缺铁性贫血(IDA)。与其他最近研究年轻人铁状况的研究不同,这项横断面研究分析了健康年轻(18-35 岁)女性(=299)的饮食摄入和生化数据,以确定血红素铁(HI)和非血红素铁(NHI)摄入与血清铁蛋白(SF)之间的关系。还测量和考虑了饮食限制和肥胖引起的可能炎症,并使用残差法调整了能量摄入。进行了独立样本 t 检验和卡方检验,对在铁充足(IR)和 ID/IDA 参与者之间存在显著差异的因素使用一般线性模型进行了分析。ID/IDA 参与者的总能量摄入明显低于铁充足(IR)(=0.003)。较低的能量摄入也与较高的饮食限制水平相关(=0.001)。HI 和 NHI 均与 SF 呈正相关,HI 被发现是比 NHI(=0.037,=0.028)更强的预测因子(=0.128,=0.009)。该研究表明,HI 和 NHI 的摄入以及足够的膳食能量与年轻女性的正常铁状态水平相关,而节食者可能面临更低的铁状态风险更大。