Department of Chemistry, Naveen Government College, Pamgarh 495554, India.
Department of Physics, RTM Nagpur University, Nagpur 440033, India.
Talanta. 2018 Apr 1;180:1-11. doi: 10.1016/j.talanta.2017.12.031. Epub 2017 Dec 12.
Chemiluminescence (CL) techniques are extensively utilized for detection of analytes due to their high sensitivity, rapidity and selectivity. With the advent of nanotechnology and incorporation of the nanoparticles in the CL system has revolutionized the assays due to their unique optical and mechanical properties. Several CL-based reactions have been developed where these nanoparticle based CL sensors have evolved as excellent prospects for sensing in various analytical applications. This review article addresses the nanoparticles based CL detection system that are recently developed, the mechanisms has been summarized and the role of luminophors have been discussed. This article critically analyzes the optimal conditions for the CL detection along with quantitative assessment of the analytes. We have included the use of semiconductor nanoparticles, metal nanoparticles, graphene based nanostructures, mesoporous nanospheres, layered double hydroxides, clays for CL detection. The scope and application of these nanoscale material based CL system in various branches of science and technology including chemistry, biomedical applications, pharmaceutics, food, environmental and toxicological applications has been critically summarized.
化学发光（CL）技术由于其高灵敏度、快速性和选择性，被广泛用于分析物的检测。随着纳米技术的出现，将纳米粒子引入 CL 系统中，由于其独特的光学和机械性质，彻底改变了分析方法。已经开发了几种基于 CL 的反应，基于这些纳米粒子的 CL 传感器已经成为各种分析应用中传感的优秀前景。本文综述了最近开发的基于纳米粒子的 CL 检测系统，总结了其机制，并讨论了发光体的作用。本文批判性地分析了 CL 检测的最佳条件以及对分析物的定量评估。我们已经包括了半导体纳米粒子、金属纳米粒子、基于石墨烯的纳米结构、介孔纳米球、层状双氢氧化物、粘土在 CL 检测中的应用。这些基于纳米级材料的 CL 系统在化学、生物医学应用、药物学、食品、环境和毒理学应用等科学技术各个分支中的应用范围和应用已经得到了批判性的总结。
