• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Fast epi-detected broadband multiplex CARS and SHG imaging of mouse skull cells.快速表皮检测的小鼠颅骨细胞宽带多路复用相干反斯托克斯拉曼散射和二次谐波成像。
Biomed Opt Express. 2017 Dec 18;9(1):245-253. doi: 10.1364/BOE.9.000245. eCollection 2018 Jan 1.
2
Label-free tetra-modal molecular imaging of living cells with CARS, SHG, THG and TSFG (coherent anti-Stokes Raman scattering, second harmonic generation, third harmonic generation and third-order sum frequency generation).利用相干反斯托克斯拉曼散射（CARS）、二次谐波产生（SHG）、三次谐波产生（THG）和三阶和频产生（TSFG）对活细胞进行无标记四模态分子成像。
Opt Express. 2012 Apr 23;20(9):9551-7. doi: 10.1364/OE.20.009551.
3
Visualizing intra-medulla lipids in human hair using ultra-multiplex CARS, SHG, and THG microscopy.利用超多重 CARS、SHG 和 THG 显微镜观察人发内髓质脂质。
Analyst. 2021 Feb 21;146(4):1163-1168. doi: 10.1039/d0an01880e. Epub 2021 Jan 5.
4
Expanding multimodal microscopy by high spectral resolution coherent anti-Stokes Raman scattering imaging for clinical disease diagnostics.通过高光谱分辨率相干反斯托克斯拉曼散射成像扩展多模态显微镜，用于临床疾病诊断。
Anal Chem. 2013 Jul 16;85(14):6703-15. doi: 10.1021/ac400570w. Epub 2013 Jul 2.
5
Imaging skeletal muscle using second harmonic generation and coherent anti-Stokes Raman scattering microscopy.利用二次谐波产生和相干反斯托克斯拉曼散射显微镜对骨骼肌进行成像。
Biomed Opt Express. 2011 Apr 27;2(5):1366-76. doi: 10.1364/BOE.2.001366.
6
Implementation of a Coherent Anti-Stokes Raman Scattering (CARS) System on a Ti:Sapphire and OPO Laser Based Standard Laser Scanning Microscope.基于钛宝石和光学参量振荡器（OPO）激光器的标准激光扫描显微镜上的相干反斯托克斯拉曼散射（CARS）系统的实现
J Vis Exp. 2016 Jul 17(113). doi: 10.3791/54262.
7
Dual CARS and SHG image acquisition scheme that combines single central fiber and multimode fiber bundle to collect and differentiate backward and forward generated photons.双相干反斯托克斯拉曼散射（CARS）和二次谐波产生（SHG）图像采集方案，该方案结合了单根中心光纤和多模光纤束，以收集和区分向后和向前产生的光子。
Biomed Opt Express. 2016 May 16;7(6):2202-18. doi: 10.1364/BOE.7.002202. eCollection 2016 Jun 1.
8
In vivo coherent anti-Stokes Raman scattering imaging of sciatic nerve tissue.坐骨神经组织的体内相干反斯托克斯拉曼散射成像
J Microsc. 2007 Feb;225(Pt 2):175-82. doi: 10.1111/j.1365-2818.2007.01729.x.
9
Chemical imaging by single pulse interferometric coherent anti-stokes Raman scattering microscopy.单脉冲干涉相干反斯托克斯拉曼散射显微镜的化学成像
J Phys Chem B. 2006 Mar 23;110(11):5196-204. doi: 10.1021/jp057493k.
10
Multimodal nonlinear optical imaging of collagen arrays.胶原蛋白阵列的多模态非线性光学成像
J Struct Biol. 2008 Oct;164(1):140-5. doi: 10.1016/j.jsb.2008.07.002. Epub 2008 Jul 11.

引用本文的文献

1
Learned end-to-end high-resolution lensless fiber imaging towards real-time cancer diagnosis.端到端的高分辨率无透镜光纤成像技术，实现实时癌症诊断。
Sci Rep. 2022 Nov 7;12(1):18846. doi: 10.1038/s41598-022-23490-5.
2
Coherent anti-Stokes Raman scattering cell imaging and segmentation with unsupervised data analysis.基于无监督数据分析的相干反斯托克斯拉曼散射细胞成像与分割
Front Cell Dev Biol. 2022 Aug 16;10:933897. doi: 10.3389/fcell.2022.933897. eCollection 2022.
3
Murine Metatarsus Bone and Joint Collagen-I Fiber Morphologies and Networks Studied With SHG Multiphoton Imaging.利用二次谐波产生多光子成像研究小鼠跖骨和关节的I型胶原纤维形态及网络结构
Front Bioeng Biotechnol. 2021 Jun 11;9:608383. doi: 10.3389/fbioe.2021.608383. eCollection 2021.
4
Multiplex coherent anti-Stokes Raman scattering highlights state of chromatin condensation in CH region.多重相干反斯托克斯拉曼散射突出了 CH 区域染色质凝聚的状态。
Sci Rep. 2019 Sep 25;9(1):13862. doi: 10.1038/s41598-019-50453-0.
5
Selective femtosecond laser ablation via two-photon fluorescence imaging through a multimode fiber.通过多模光纤进行双光子荧光成像的选择性飞秒激光烧蚀
Biomed Opt Express. 2019 Jan 7;10(2):423-433. doi: 10.1364/BOE.10.000423. eCollection 2019 Feb 1.

本文引用的文献

1
Label-free nonlinear optical microscopy detects early markers for osteogenic differentiation of human stem cells.无标记非线性光学显微镜检测人干细胞成骨分化的早期标志物。
Sci Rep. 2016 May 26;6:26716. doi: 10.1038/srep26716.
2
Contributions of Raman spectroscopy to the understanding of bone strength.拉曼光谱对理解骨强度的贡献。
Bonekey Rep. 2015 Jan 7;4:620. doi: 10.1038/bonekey.2014.115. eCollection 2015.
3
Advances in engineering of high contrast CARS imaging endoscopes.高对比度相干反斯托克斯拉曼散射（CARS）成像内窥镜的工程进展。
Opt Express. 2014 Oct 20;22(21):25053-64. doi: 10.1364/OE.22.025053.
4
Multimodal and multiplex spectral imaging of rat cornea ex vivo using a white-light laser source.使用白光源对大鼠角膜进行离体多模态和多光谱成像。
J Biophotonics. 2015 Sep;8(9):705-13. doi: 10.1002/jbio.201400059. Epub 2014 Nov 6.
5
Quantitative, label-free characterization of stem cell differentiation at the single-cell level by broadband coherent anti-Stokes Raman scattering microscopy.通过宽带相干反斯托克斯拉曼散射显微镜在单细胞水平上对干细胞分化进行定量、无标记表征。
Tissue Eng Part C Methods. 2014 Jul;20(7):562-9. doi: 10.1089/ten.TEC.2013.0472. Epub 2013 Dec 31.
6
Multicomponent chemical imaging of pharmaceutical solid dosage forms with broadband CARS microscopy.采用宽带 CARS 显微镜对药物固体制剂进行多组分化学成像。
Anal Chem. 2013 Sep 3;85(17):8102-11. doi: 10.1021/ac400671p. Epub 2013 Aug 20.
7
Label-free tetra-modal molecular imaging of living cells with CARS, SHG, THG and TSFG (coherent anti-Stokes Raman scattering, second harmonic generation, third harmonic generation and third-order sum frequency generation).利用相干反斯托克斯拉曼散射（CARS）、二次谐波产生（SHG）、三次谐波产生（THG）和三阶和频产生（TSFG）对活细胞进行无标记四模态分子成像。
Opt Express. 2012 Apr 23;20(9):9551-7. doi: 10.1364/OE.20.009551.
8
Raman spectroscopy and CARS microscopy of stem cells and their derivatives.干细胞及其衍生物的拉曼光谱和相干反斯托克斯拉曼散射显微镜技术
J Raman Spectrosc. 2011 Oct;42(10):1864-1870. doi: 10.1002/jrs.2975.
9
Raman spectroscopic monitoring of the osteogenic differentiation of human mesenchymal stem cells.拉曼光谱监测人骨髓间充质干细胞的成骨分化。
Analyst. 2011 Jun 21;136(12):2471-81. doi: 10.1039/c1an15167c. Epub 2011 May 4.
10
Video-rate molecular imaging in vivo with stimulated Raman scattering.利用受激拉曼散射进行体内视频速率分子成像。
Science. 2010 Dec 3;330(6009):1368-70. doi: 10.1126/science.1197236.

快速表皮检测的小鼠颅骨细胞宽带多路复用相干反斯托克斯拉曼散射和二次谐波成像。

Fast epi-detected broadband multiplex CARS and SHG imaging of mouse skull cells.

作者信息

Capitaine Erwan, Moussa Nawel Ould, Louot Christophe, Bardet Sylvia M, Kano Hideaki, Duponchel Ludovic, Lévêque Philippe, Couderc Vincent, Leproux Philippe

机构信息

XLIM UMR 7252, CNRS-Université de Limoges, 123 avenue Albert Thomas, 87060 Limoges Cedex, France.

Department of Applied Physics, Graduate School of Pure and Applied Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8573, Japan.

出版信息

Biomed Opt Express. 2017 Dec 18;9(1):245-253. doi: 10.1364/BOE.9.000245. eCollection 2018 Jan 1.

DOI:10.1364/BOE.9.000245
PMID:29359100
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5772578/
Abstract

We present a bimodal imaging system able to obtain epi-detected mutiplex coherent anti-Stokes Raman scattering (M-CARS) and second harmonic generation (SHG) signals coming from biological samples. We studied a fragment of mouse parietal bone and could detect broadband anti-Stokes and SHG responses originating from bone cells and collagen respectively. In addition we compared two post-processing methods to retrieve the imaginary part of the third-order nonlinear susceptibility related to the spontaneous Raman scattering.

摘要

我们展示了一种双峰成像系统，该系统能够获取来自生物样本的外差检测多重相干反斯托克斯拉曼散射（M-CARS）和二次谐波产生（SHG）信号。我们研究了小鼠顶骨的一个片段，能够分别检测到源自骨细胞和胶原蛋白的宽带反斯托克斯和SHG响应。此外，我们比较了两种后处理方法，以检索与自发拉曼散射相关的三阶非线性极化率的虚部。