Zaidi Sahar, Hussain Showket, Verma Shalini, Veqar Zubia, Khan Asiya, Nazir Sheeraz Un, Singh Neha, Moiz Jamal Ali, Tanwar Pranay, Srivastava Anurag, Rath G K, Mehrotra Ravi
Centre for Physiotherapy and Rehabilitation Sciences, Jamia Millia Islamia (Central University), New Delhi, India.
National Institute of Cancer Prevention and Research, Indian Council of Medical Research (NICPR-ICMR), New Delhi, India.
Front Oncol. 2018 Jan 11;7:326. doi: 10.3389/fonc.2017.00326. eCollection 2017.
Breast cancer (BC) is the most common cancer diagnosed in women and the second most common cancer overall, ranking as the fifth cause of death from cancer. The chronicity of the disease produces long-term physiological and psychological manifestations, which adversely affect the quality of life of the individual. The primary treatment while managing cancer presents with various debilitating side effects. With the recent advances in treatment techniques that have improved the survival rate, patients suffer from continuing posttreatment complications. Patients seem to cope well with the stress of treatment of BC and sustain a normal life; however, the deterioration in physical well-being makes the patient functionally inefficient. Exercise has been proven to be an effective, safe, and feasible tool in combating the adverse effects of treatment, prevents complications and decreases the risk of BC-specific mortality. This review briefly presents an overview of the burden of the disease and its management strategies. Owing to the heterogeneity of the population and the multitude of therapies they receive, the response of each patient to treatment is different and so is the magnitude of adverse effects. The review discusses the late sequelae following treatment and evidence supporting the role of physical activity in their management. In conclusion, there is a need for personalized physical activity plans to be developed to suit the individual and their circumstances.
乳腺癌（BC）是女性中最常被诊断出的癌症，也是总体上第二常见的癌症，是癌症死亡的第五大原因。该疾病的慢性病程会产生长期的生理和心理表现，对个体的生活质量产生不利影响。治疗癌症的主要方法会带来各种使人虚弱的副作用。随着治疗技术的最新进展提高了生存率，患者仍遭受持续的治疗后并发症。患者似乎能很好地应对乳腺癌治疗的压力并维持正常生活；然而，身体状况的恶化使患者功能效率低下。运动已被证明是对抗治疗不良反应、预防并发症和降低乳腺癌特异性死亡率风险的有效、安全且可行的工具。本综述简要概述了该疾病的负担及其管理策略。由于人群的异质性以及他们接受的多种治疗方法，每位患者对治疗的反应不同，不良反应的程度也不同。该综述讨论了治疗后的晚期后遗症以及支持体育活动在其管理中作用的证据。总之，需要制定个性化的体育活动计划以适合个体及其情况。
