Division of Pulmonary Critical Care and Sleep Medicine, Department of Internal Medicine, University of Texas Medical Branch, 301 University Blvd, Galveston, TX, 77555, USA.
Division of Allergy/Immunology, Department of Pediatric Medicine, Perelman School of Medicine at the University of Pennsylvania, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Curr Allergy Asthma Rep. 2018 Jan 29;18(1):3. doi: 10.1007/s11882-018-0757-y.
Chronic respiratory diseases affecting adults and children are widely prevalent, so lung function testing is imperative for diagnosis and management. Spirometry is the traditional standard measure of lung function; however, certain groups of patients are unable to provide accurate and reproducible exhalation maneuvers. Consequently, the impedance oscillometry system (IOS) has been developed as an effort, independent technique to assess airway function in children and the elderly. To better understand this emerging modality, the following review will compare IOS with spirometry, examine the function of the device, provide interpretation strategies, and discuss the evidence supporting its use in adults and children with chronic lung disease.
In a population of symptomatic adults with suspected COPD, impedance oscillometry resistance measurements correlate with FEV and lung resistance increases with the severity of airflow limitation. In patients with asthma, IOS is a sensitive measure of airway hyperresponsiveness and bronchodilator response. Impedance oscillometry is evolving as an alternative measure to assess lung function pediatric and adult populations.
影响成人和儿童的慢性呼吸系统疾病广泛流行,因此肺功能测试对于诊断和管理至关重要。肺活量计是肺功能的传统标准测量方法;然而,某些患者群体无法提供准确和可重复的呼气动作。因此,已经开发出阻抗振荡系统(IOS)作为一种独立的技术,用于评估儿童和老年人的气道功能。为了更好地理解这种新兴模式,以下综述将比较 IOS 与肺活量计,检查设备的功能,提供解释策略,并讨论其在患有慢性肺部疾病的成人和儿童中的应用证据。
在有疑似 COPD 的症状性成年人人群中,阻抗振荡测量的阻力与 FEV 相关,并且肺阻力随着气流受限的严重程度而增加。在哮喘患者中,IOS 是气道高反应性和支气管扩张剂反应的敏感测量方法。阻抗振荡测量法作为一种替代测量方法,正在不断发展,用于评估儿科和成人人群的肺功能。