Prophylactic and immune modulatory influences of Linn. in broilers exposed to biological challenge.

BACKGROUND AND AIM

Prophylaxis and disease prevention is an essential strategy among biorisk management in poultry farms that stimulate and maintain the birds' immunity. The aim of this study was to investigate the prophylactic, and immune-stimulant influence of Linn. in broilers under biological stress.

MATERIALS AND METHODS

A total of 250 1-day-old (ross) chicks were divided into 5 groups; four of which were supplemented with 1.4%, 2.8%, 4.2%, and 5.6% Linn., respectively. The four supplemented groups were challenged with O:H 1.5×10 at a 14 day old. A total of 1050 samples (150 serum, 150 swab, and 750 organ samples) were collected and examined.

RESULTS

A highly significant increase (p<0.01) in 5.6% Linn. supplemented group in performance traits (body weight, weight gain, and performance index), biochemical parameters (proteinogram, liver enzymes, and creatinine), immunoglobulins concentration, and immune organs' weight. Meanwile, liver showed improvement of histoarchitecture without fibrosis. Heart showed a mild pericarditis with a mild degree of hydropic degeneration. Bursa, thymus, and spleen showed lymphoid hyperplasia.

CONCLUSION

A concentration of 5.6% Linn. in broiler's feed can improve the immune response and subsequent resistance of broilers against diseases.