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Linn. 对遭受生物挑战的肉鸡的预防和免疫调节作用。

Prophylactic and immune modulatory influences of Linn. in broilers exposed to biological challenge.

作者信息

Soliman Essam S, Hamad Rania T, Ahmed Amira

机构信息

Department of Animal Hygiene, Zoonosis and Animal Behavior, Faculty of Veterinary Medicine, Suez Canal University, Ismailia 41522, Egypt.

Department of Pathology, Faculty of Veterinary Medicine, Suez Canal University, Ismailia 41522, Egypt.

出版信息

Vet World. 2017 Dec;10(12):1447-1455. doi: 10.14202/vetworld.2017.1447-1455. Epub 2017 Dec 12.

DOI:10.14202/vetworld.2017.1447-1455
PMID:29391685
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5771169/
Abstract

BACKGROUND AND AIM

Prophylaxis and disease prevention is an essential strategy among biorisk management in poultry farms that stimulate and maintain the birds' immunity. The aim of this study was to investigate the prophylactic, and immune-stimulant influence of Linn. in broilers under biological stress.

MATERIALS AND METHODS

A total of 250 1-day-old (ross) chicks were divided into 5 groups; four of which were supplemented with 1.4%, 2.8%, 4.2%, and 5.6% Linn., respectively. The four supplemented groups were challenged with O:H 1.5×10 at a 14 day old. A total of 1050 samples (150 serum, 150 swab, and 750 organ samples) were collected and examined.

RESULTS

A highly significant increase (p<0.01) in 5.6% Linn. supplemented group in performance traits (body weight, weight gain, and performance index), biochemical parameters (proteinogram, liver enzymes, and creatinine), immunoglobulins concentration, and immune organs' weight. Meanwile, liver showed improvement of histoarchitecture without fibrosis. Heart showed a mild pericarditis with a mild degree of hydropic degeneration. Bursa, thymus, and spleen showed lymphoid hyperplasia.

CONCLUSION

A concentration of 5.6% Linn. in broiler's feed can improve the immune response and subsequent resistance of broilers against diseases.

摘要

背景与目的

预防和疾病防控是家禽养殖场生物风险管理中的一项重要策略，可刺激和维持家禽的免疫力。本研究旨在调查[植物名称未给出，原文为 Linn.]对处于生物应激状态下的肉鸡的预防及免疫刺激作用。

材料与方法

总共250只1日龄（罗斯品种）雏鸡被分为5组；其中4组分别添加1.4%、2.8%、4.2%和5.6%的[植物名称未给出，原文为 Linn.]。这4个添加组在14日龄时用[细菌名称未给出，原文为 O:H 1.5×10]进行攻毒。总共收集并检测了1050份样本（150份血清、150份拭子和750份器官样本）。

结果

在性能指标（体重、增重和性能指数）、生化参数（蛋白图谱、肝酶和肌酐）、免疫球蛋白浓度以及免疫器官重量方面，添加5.6%[植物名称未给出，原文为 Linn.]的组有极显著增加（p<0.01）。同时，肝脏组织结构改善，无纤维化。心脏显示轻度心包炎，伴有轻度水样变性。法氏囊、胸腺和脾脏显示淋巴样增生。

结论

在肉鸡饲料中添加5.6%的[植物名称未给出，原文为 Linn.]可提高肉鸡的免疫反应及随后对疾病的抵抗力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ee6/5771169/22325ce335cb/VetWorld-10-1447-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ee6/5771169/86748454a899/VetWorld-10-1447-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ee6/5771169/b4c52b83eaab/VetWorld-10-1447-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ee6/5771169/c853d52a0300/VetWorld-10-1447-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ee6/5771169/fc886a9dede4/VetWorld-10-1447-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ee6/5771169/22325ce335cb/VetWorld-10-1447-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ee6/5771169/86748454a899/VetWorld-10-1447-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ee6/5771169/b4c52b83eaab/VetWorld-10-1447-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ee6/5771169/c853d52a0300/VetWorld-10-1447-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ee6/5771169/fc886a9dede4/VetWorld-10-1447-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ee6/5771169/22325ce335cb/VetWorld-10-1447-g005.jpg

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