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卢旺达丙型肝炎控制:国家应对框架。

Controlling hepatitis C in Rwanda: a framework for a national response.

机构信息

Rwanda Biomedical Center, Kigali, Rwanda.

Partners in Health, Inshuti Mu Buzima, KG 9 Avenue, Plot No. 46, Kigali, Rwanda.

出版信息

Bull World Health Organ. 2018 Jan 1;96(1):51-58. doi: 10.2471/BLT.16.183772. Epub 2017 Nov 27.

Abstract

With the introduction of direct-acting antiviral drugs, treatment of hepatitis C is both highly effective and tolerable. Access to treatment for patients, however, remains limited in low- and middle-income countries due to the lack of supportive health infrastructure and the high cost of treatment. Poorer countries are being encouraged by international bodies to organize public health responses that would facilitate the roll-out of care and treatment on a national scale. Yet few countries have documented formal plans and policies. Here, we outline the approach taken in Rwanda to a public health framework for hepatitis C control and care within the World Health Organization hepatitis health sector strategy. This includes the development and implementation of policies and programmes, prevention efforts, screening capacity, treatment services and strategic information systems. We highlight key successes by the national programme for the control and management of hepatitis C: establishment of national governance and planning; development of diagnostic capacity; approval and introduction of direct-acting antiviral treatments; training of key personnel; generation of political will and leadership; and fostering of key strategic partnerships. Existing challenges and next steps for the programme include developing a detailed monitoring and evaluation framework and tools for monitoring of viral hepatitis. The government needs to further decentralize care and integrate hepatitis C management into routine clinical services to provide better access to diagnosis and treatment for patients. Introducing rapid diagnostic tests to public health-care facilities would help to increase case-finding. Increased public and private financing is essential to support care and treatment services.

摘要

随着直接作用抗病毒药物的引入,丙型肝炎的治疗既高效又耐受。然而,由于缺乏支持性卫生基础设施和治疗费用高昂,中低收入国家的患者获得治疗的机会仍然有限。国际机构鼓励较贫穷国家组织公共卫生应对措施,以便在国家范围内推广护理和治疗。然而,很少有国家有正式的计划和政策文件。在这里,我们概述了卢旺达在世界卫生组织丙型肝炎卫生部门战略框架内采取的公共卫生控制和护理丙型肝炎的方法。这包括制定和实施政策和方案、预防工作、筛查能力、治疗服务和战略信息系统。我们强调了国家丙型肝炎控制和管理规划的主要成功之处:建立国家治理和规划;发展诊断能力;批准和引入直接作用抗病毒药物治疗;培训关键人员;产生政治意愿和领导力;以及培养关键战略伙伴关系。该规划目前面临的挑战和下一步措施包括制定详细的监测和评估框架以及监测病毒性肝炎的工具。政府需要进一步将护理工作去中心化,并将丙型肝炎管理纳入常规临床服务,为患者提供更好的诊断和治疗机会。在公共卫生保健机构引入快速诊断测试将有助于增加病例发现。增加公共和私人资金对于支持护理和治疗服务至关重要。

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