Division of Allergy and Immunology, Boston Children's Hospital, Boston, Massachusetts; Harvard Medical School, Boston, Massachusetts.
Division of Allergy and Immunology, Boston Children's Hospital, Boston, Massachusetts; Harvard Medical School, Boston, Massachusetts.
Ann Allergy Asthma Immunol. 2018 May;120(5):482-487. doi: 10.1016/j.anai.2018.01.028.
To provide a comprehensive overview of common school exposures and the association between school exposures and pediatric asthma morbidity.
A comprehensive literature review was performed using PubMed.
Full-length, peer-reviewed studies published in English were considered for review. In vivo, in vitro, and animal studies were excluded. Studies of school exposure to cockroach, mouse, dust mite, dog, cat, molds, pollution, and endotoxin associated with asthma and asthma morbidity were considered.
The current literature establishes an association between school exposure and pediatric asthma morbidity. There is a need for ongoing research to evaluate the effects of school-based environmental interventions on asthma morbidity.
It is evident that the indoor school environment is a significant reservoir of allergens, molds, pollutants, and endotoxin and that there is an association between school exposure and pediatric asthma morbidity. School-based interventions have the potential for substantial individual, community, and public health benefit. It is important that researchers continue to study the health effects associated with school exposures and assess cost-effectiveness of multifaceted school-based interventions.
全面概述常见的学校暴露因素以及学校暴露因素与儿童哮喘发病率之间的关系。
使用 PubMed 进行了全面的文献回顾。
考虑了全文、同行评审、以英语发表的研究。排除了体内、体外和动物研究。研究了与哮喘和哮喘发病率相关的蟑螂、老鼠、尘螨、狗、猫、霉菌、污染和内毒素的学校暴露。
目前的文献确立了学校暴露与儿童哮喘发病率之间的关联。需要进行持续的研究，以评估基于学校的环境干预对哮喘发病率的影响。
显然，室内学校环境是过敏原、霉菌、污染物和内毒素的重要储存库，学校暴露与儿童哮喘发病率之间存在关联。基于学校的干预措施有可能对个人、社区和公共健康产生重大影响。研究人员继续研究与学校暴露相关的健康影响并评估多方面基于学校的干预措施的成本效益非常重要。
