Spinner Christoph D, Müller Matthias C, Lange Berit
Klinik und Poliklinik für Innere Medizin II, Klinikum rechts der Isar der Technischen Universität München, München.
Universitätsklinikum Freiburg, Abteilung für Infektiologie, Klinik für Innere Medizin II, Freiburg i. Br.
Dtsch Med Wochenschr. 2018 Feb;143(3):157-160. doi: 10.1055/s-0043-123608. Epub 2018 Feb 6.
Bedside laboratory procedures so called "point of care testing - POCT" plays an emerging role in clinical routine practice. While glucose or urine protein screening has been established since a while, newer lateral flow assays (LFID), mostly as rapid diagnostic tests (RDT), play and upcoming role, as well as nucleic amplification based and micro carrier based systems. Hereby an accurate and precise diagnostic allows clinical decisions; in infectious diseases as well as other disciplines in medicine. All test are limited by sensitivity and specifity. Moreover, pre- and post-analytic handling also influences the test results. All results need to be assessed by a trained medical doctor.
所谓的“即时检验(POCT)”床边实验室程序在临床常规实践中发挥着越来越重要的作用。虽然血糖或尿蛋白筛查已经开展了一段时间,但更新的侧向流动分析(LFID),大多作为快速诊断测试(RDT),以及基于核酸扩增和基于微载体的系统,正发挥着越来越重要的作用。准确而精确的诊断有助于临床决策,在传染病以及医学的其他学科中都是如此。所有检测都受到灵敏度和特异性的限制。此外,分析前和分析后的处理也会影响检测结果。所有结果都需要由经过培训的医生进行评估。