2013 年中国南方一只苍鹭携带的高致病性 H5N6 流感病毒的遗传和系统进化分析。
The genetic and phylogenetic analysis of a highly pathogenic influenza A H5N6 virus from a heron, southern China, 2013.
机构信息
College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China; Key Laboratory of Zoonosis Prevention and Control of Guangdong Province, Guangzhou 510642, China.
Shantou University Medical College, Shantou 515041, China.
出版信息
Infect Genet Evol. 2018 Apr;59:72-74. doi: 10.1016/j.meegid.2018.01.028. Epub 2018 Jan 31.
The H5N6 highly pathogenic avian influenza viruses (HPAIVs) have circulated within poultry in China since 2013. Infections of H5N6 in wild birds were reported since 2014. In order to investigate the infection history of H5N6 in wild birds, we conducted a retrospective analysis of H5 positive wild bird samples collected in 2013, the year H5N6 was discovered in poultry. We isolated a new HPAI H5N6 virus from a dead heron collected in 2013. The virus had high identity in all eight gene sequences to those collected from poultry in 2013 (for example, A/chicken/Shenzhen/1845/2013, 99.1%-99.7%). Our findings revealed that H5N6 HPAIVs infected wild birds in southern China since the emergence of H5N6 in poultry in 2013. The co-circulation of H5N6 between wild birds and poultry is very close, and should raise our attention more.
自 2013 年以来，H5N6 高致病性禽流感病毒（HPAIVs）一直在中国家禽中传播。自 2014 年以来，已报告野生鸟类感染 H5N6 病例。为了调查野生鸟类中 H5N6 的感染史，我们对 2013 年发现家禽 H5N6 时收集的 H5 阳性野生鸟类样本进行了回顾性分析。我们从 2013 年采集的一只死苍鹭中分离出一种新型 HPAI H5N6 病毒。该病毒的所有八个基因序列与 2013 年从家禽中采集的病毒高度一致（例如，A/chicken/Shenzhen/1845/2013，99.1%-99.7%）。我们的研究结果表明，自 2013 年家禽中出现 H5N6 以来，H5N6 HPAIVs 已感染中国南方的野生鸟类。H5N6 在野生鸟类和家禽之间的共同传播非常密切，应该引起我们更多的关注。
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