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基于韩国国家健康和营养检查调查 III-VI 的韩国成年人糖尿病患病率趋势。

Trends in diabetes prevalence among Korean adults based on Korean National Health and Nutrition Examination Surveys III-VI.

机构信息

Department of Family Medicine, Chungbuk National University Hospital, Cheongju, Republic of Korea.

Department of Family Medicine, Chungbuk National University Hospital, Cheongju, Republic of Korea; Department of Family Medicine, Chungbuk National University College of Medicine, Cheongju, Republic of Korea.

出版信息

Diabetes Res Clin Pract. 2018 Apr;138:57-65. doi: 10.1016/j.diabres.2018.01.013. Epub 2018 Feb 2.

Abstract

AIMS

The purpose of this study was to investigate trends in diabetic prevalence over the past 11 years using Korea National Health and Nutrition Examination Survey (KNHANES) data. In addition, we aimed to examine trends in diagnosed and undiagnosed diabetes after stratification.

METHODS

We used data from the KNHANES III (2005), IV (2007-2009), V (2010-2012), and VI (2013-2015). 46,157 participants were included in this study. Diabetes was defined as follows: (1) an answer of 'yes' to whether the participants had ever been diagnosed with diabetes by a physician, (2) fasting plasma glucose (FPG) ≥126 mg/dL, or (3) taking oral hypoglycemic agents or insulin. All sampling and weight variables were stratified, and analysis to account for the complex sampling design. The prevalence of diabetes was standardized by the 2005 Korean Housing Census.

RESULTS

In men, the crude prevalence of total and undiagnosed diabetes were significantly increased with KNHANES phase (P for trend = 0.002 and 0.004, respectively). The age-standardized prevalence of total, diagnosed and undiagnosed diabetes of both sexes increased with the KNHANES phase (all P for trend < 0.001). Compared with the KNHANES III, the age-adjusted odds ratios (ORs) for the crude-prevalence of undiagnosed diabetes in KNHANES IV, V, and VI were 1.00 (0.72-1.41), 1.08 (0.78-1.51), and 1.42 (1.04-1.96) for men.

CONCLUSIONS

The prevalence of total, diagnosed and undiagnosed diabetes steadily increased and public efforts should focus on screening for the detection of diabetes, especially in men.

摘要

目的

本研究旨在利用韩国国民健康营养调查(KNHANES)数据,调查过去 11 年糖尿病患病率的变化趋势。此外,我们还旨在通过分层来检查确诊和未确诊糖尿病的趋势。

方法

我们使用了 KNHANES III(2005 年)、IV(2007-2009 年)、V(2010-2012 年)和 VI(2013-2015 年)的数据。共有 46157 名参与者纳入本研究。糖尿病的定义如下:(1)参与者是否曾被医生诊断为糖尿病的回答为“是”;(2)空腹血糖(FPG)≥126mg/dL;或(3)服用口服降糖药或胰岛素。所有抽样和体重变量均进行分层,并进行分析以考虑到复杂的抽样设计。糖尿病的患病率按 2005 年韩国住房普查进行标准化。

结果

在男性中,总糖尿病和未确诊糖尿病的粗患病率随着 KNHANES 阶段的变化而显著增加(趋势 P 值分别为 0.002 和 0.004)。男女两性的总糖尿病、确诊糖尿病和未确诊糖尿病的年龄标准化患病率均随 KNHANES 阶段的变化而增加(所有趋势 P 值均<0.001)。与 KNHANES III 相比,KNHANES IV、V 和 VI 中未确诊糖尿病的粗患病率的年龄调整比值比(OR)分别为 1.00(0.72-1.41)、1.08(0.78-1.51)和 1.42(1.04-1.96)。

结论

总糖尿病、确诊糖尿病和未确诊糖尿病的患病率稳步上升,应加大力度进行糖尿病筛查,尤其是男性。

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