Cancer Data Center, National Cancer Control Institute, National Cancer Center, Gyeonggi-do, Goyang-si 10408, Korea.
Graduate School of Cancer Science and Policy, National Cancer Center, Gyeonggi-do, Goyang-si 10408, Korea.
Int J Environ Res Public Health. 2021 Jan 29;18(3):1195. doi: 10.3390/ijerph18031195.
In this cross-sectional study, we investigated the baseline risk factors of diabetes mellitus (DM) in patients with undiagnosed DM (UDM). We utilized the Korean National Health and Nutrition Examination Survey (KNHANES) 2010-2017 data. Data regarding the participants' demographic characteristics, health status, health determinants, healthcare accessibility, and laboratory tests were gathered to explore the differences between the DM, UDM, and without-DM groups. Among the 64,759 individuals who participated in the KNHANES 2010-2017, 32,611 individuals aged ≥20 years with fasting plasma glucose levels of <100 or ≥126 mg/dL were selected. The odds ratios (ORs) regarding family history of diabetes and the performance of national health and cancer screening tests were lower in the UDM group than in the DM group (adjusted OR: 0.54; 95% confidence interval (CI): 0.43, 0.66; adjusted OR: 0.74; 95% CI: 0.62, 0.89; adjusted OR: 0.71; 95% CI: 0.60, 0.85). The ORs of hypertension and obesity were higher in the UDM group than in the DM group (adjusted OR: 1.32; 95% CI: 1.06, 1.64; adjusted OR: 1.80; 95% CI: 1.37, 2.36, respectively). Patients with UDM were more likely to be exposed to DM-related risk factors than those with and without DM. Public health interventions to prevent UDM development are necessary.
在这项横断面研究中，我们调查了未诊断糖尿病（UDM）患者的糖尿病（DM）基线风险因素。我们利用了韩国国家健康和营养检查调查（KNHANES）2010-2017 年的数据。收集了有关参与者的人口统计学特征、健康状况、健康决定因素、医疗保健可及性和实验室检查的数据，以探讨 DM、UDM 和无 DM 组之间的差异。在参与 KNHANES 2010-2017 年的 64759 人中，选择了 32611 名年龄≥20 岁、空腹血糖水平<100 或≥126mg/dL 的个体。与 DM 组相比，UDM 组的糖尿病家族史和国家健康和癌症筛查测试的比值比（OR）较低（调整 OR：0.54；95%置信区间（CI）：0.43，0.66；调整 OR：0.74；95%CI：0.62，0.89；调整 OR：0.71；95%CI：0.60，0.85）。与 DM 组相比，UDM 组的高血压和肥胖的 OR 更高（调整 OR：1.32；95%CI：1.06，1.64；调整 OR：1.80；95%CI：1.37，2.36）。与有和无 DM 者相比，UDM 患者更有可能接触到与 DM 相关的危险因素。需要进行公共卫生干预以预防 UDM 的发生。
