Key Laboratory of Interfacial Reaction & Sensing Analysis in Universities of Shandong, University of Jinan, Jinan 250022, PR China.
Key Laboratory of Interfacial Reaction & Sensing Analysis in Universities of Shandong, University of Jinan, Jinan 250022, PR China.
Biosens Bioelectron. 2018 May 30;106:7-13. doi: 10.1016/j.bios.2018.01.051. Epub 2018 Jan 31.
A novel photoelectrochemical (PEC) aptasensor based on cerium (Ce) doped CdS modified graphene (G)/BiYWO was designed, which exhibits enhanced PEC intensity compared with pure BiYWO, G/BiYWO and BiYWO/Ce:CdS. In this scenario, ascorbic acid (AA) was exploited as an efficient and non-poisonous electron donor for scavenging photogenerated holes. The doping of Ce in CdS promoted its visible light absorption range and facilitated the charge transfer rate as well as hindered the h/e recombination. Moreover, the combination of G further promoted the electron carrier separation and transfer process due to its excellent electron collection and shuttling characteristic. Thus, the G/BiYWO/Ce:CdS heterostructure was successfully served as a matrix for the PEC detection of tetracycline (Tc) at 0 V (vs Hg/HgCl). Under optimal conditions, the PEC aptasensor could offer a sensitive and specific detection limit (3 S/N) of Tc down to 0.01 ng/mL, as well as acceptable reproducibility, selectivity and storage stability, which opened up a promising pathway for the development of PEC biosensors.
一种基于掺杂铈的硫化镉修饰的石墨烯（G）/BiYWO 的光电化学（PEC）适体传感器被设计出来，与纯 BiYWO、G/BiYWO 和 BiYWO/Ce:CdS 相比，其 PEC 强度得到了增强。在这种情况下，抗坏血酸（AA）被用作一种高效且无毒的电子供体，用于清除光生空穴。Ce 在 CdS 中的掺杂促进了其可见光吸收范围，并促进了电荷转移速率，同时抑制了 h/e 复合。此外，由于其优异的电子收集和穿梭特性，G 的结合进一步促进了电子载流子的分离和转移过程。因此，G/BiYWO/Ce:CdS 异质结成功地用作在 0 V（相对于 Hg/HgCl）下检测四环素（Tc）的 PEC 检测的基质。在最佳条件下，PEC 适体传感器可以对 Tc 进行灵敏且特异的检测，检测限（3 S/N）低至 0.01 ng/mL，并且具有可接受的重现性、选择性和存储稳定性，为 PEC 生物传感器的发展开辟了一条有前景的途径。
