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伊朗东南部疫苗接种运动 8 个月后麻疹和风疹抗体的血清阳性率。

Seroprevalence of antibodies to measles and rubella eight months after a vaccination campaign in the southeast of Iran.

机构信息

a Health Promotion Research Centre , School of Public Health, Zahedan University of Medical Sciences , Zahedan , Iran.

b Centre for Communicable Diseases Control, Ministry of Health and Medical Education , Tehran , Iran.

出版信息

Hum Vaccin Immunother. 2018 Jun 3;14(6):1412-1416. doi: 10.1080/21645515.2018.1436920. Epub 2018 Feb 26.

Abstract

Eight months after the mass immunization campaign of November 2015 against measles and rubella in the southeast of Iran, in order to evaluate the sero-immunity level of the people living in the mentioned region, a serosurvey study was performed. Using a multi-stage probability proportional to size cluster sampling, the sera of 1,056 participants, ranging from 15 months to 20 years old, were tested for measles and rubella IgG antibodies in the National Reference Laboratory at Tehran University of Medical Sciences, Tehran, Iran. The seroprevalence rates of antibodies against measles and rubella in the age groups below 16 years were respectively 98.4 and 93.2%. In the age group of 16 to 20 years, who was not the target of the mass immunization campaign, the said rates were respectively 91.7% and 87.4%. The herd immunity of the age groups below 16 years, who were the target of the campaign, is favourably high and reassuring both for measles and for rubella. Campaigns of supplementary vaccination play a substantial role for filling the gaps in the herd immunity.

摘要

2015 年 11 月,伊朗东南部开展了麻疹和风疹大规模免疫运动,8 个月后,为评估该地区居民的血清免疫水平,进行了血清学调查研究。在伊朗德黑兰的德黑兰医科大学国家参考实验室,采用多阶段概率比例大小集群抽样方法,对 1,056 名年龄在 15 个月至 20 岁的参与者的血清进行了麻疹和风疹 IgG 抗体检测。在 16 岁以下年龄组中,麻疹和风疹抗体的血清阳性率分别为 98.4%和 93.2%。在 16 至 20 岁年龄组中,该人群并非大规模免疫运动的目标人群,上述两种疾病的血清阳性率分别为 91.7%和 87.4%。针对目标人群(16 岁以下年龄组)的群体免疫水平较高,对麻疹和风疹都具有令人放心的保护效果。补充免疫接种运动对于填补群体免疫中的空白起到了重要作用。

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