Centro de Investigación en Alimentación y Desarrollo, A.C. (CIAD), Carretera a La Victoria Km. 0.6, Hermosillo, Sonora, Mexico, 83304.
Hospital Privado de Hermosillo, S.A. de C.V. (Hospital CIMA Hermosillo), Hermosillo, Sonora, México 83280.
J Dairy Sci. 2018 Apr;101(4):2819-2825. doi: 10.3168/jds.2017-13189. Epub 2018 Feb 7.
The blood pressure-lowering effect of fermented milk with Lactococcus lactis NRRL B-50571 was evaluated in a double-blind randomized controlled clinical trial with prehypertensive subjects. Participants were randomized into 2 groups (n = 18 each group): one group treated with fermented milk with Lactococcus lactis NRRL B-50571 and a control group treated with artificially acidified milk. Results revealed that during daily consumption of fermented milk for 5 wk, systolic [(116.55 ± 12.26 mmHg vs. 124.77 ± 11.04 mmHg) and diastolic blood pressure (80.7 ± 9 vs. 84.5 ± 8.5 mmHg)] from the fermented milk group was lower than the control group. Additionally, triglyceride, total cholesterol, and low-density lipoprotein in blood serum were lower in the fermented milk group than in the control group. Results demonstrated that daily consumption of fermented milk with Lactococcus lactis (NRRL B-50571) had a blood pressure-lowering effect on prehypertensive subjects. Regular consumption of this product may be used as a potential functional food.
采用双盲随机对照临床试验，评估了具有 Lactococcus lactis NRRL B-50571 的发酵乳对高血压前期受试者的降压效果。将参与者随机分为 2 组（每组 18 人）：一组用具有 Lactococcus lactis NRRL B-50571 的发酵乳治疗，对照组用人工酸化乳治疗。结果显示，在连续 5 周每天食用发酵乳期间，发酵乳组的收缩压[（116.55 ± 12.26mmHg 比 124.77 ± 11.04mmHg）和舒张压（80.7 ± 9mmHg 比 84.5 ± 8.5mmHg）]均低于对照组。此外，发酵乳组的血清甘油三酯、总胆固醇和低密度脂蛋白也低于对照组。结果表明，每日食用具有 Lactococcus lactis（NRRL B-50571）的发酵乳对高血压前期受试者具有降压作用。经常食用该产品可作为一种潜在的功能性食品。
