Sonthipet Sorawot, Ruenphet Sakchai, Takehara Kazuaki
Immunology and Virology Department, Faculty of Veterinary Medicine, Mahanakorn University of Technology, 140 Cheum-Sampan Rd., Nong Chock, Bangkok 10530, Thailand.
Laboratory of Animal Health, Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology, 3-5-8, Saiwai-cho, Fuchu-shi, Tokyo 183-8509, Japan.
J Vet Med Sci. 2018 Apr 18;80(4):568-573. doi: 10.1292/jvms.17-0599. Epub 2018 Feb 12.
An acidic agent, potassium monopersulfate (PMPS), was evaluated for bactericidal and virucidal effects against Salmonella Infantis (SI), Escherichia coli, rifampicin-resistant Salmonella Infantis (SI-rif), Newcastle disease virus (NDV), and avian influenza virus (AIV), in the absence or presence of organic materials. In addition, inactivation activity toward a virus on virus-spiked clothes was also examined. PMPS could inactivate SI, E. coli, and SI-rif even in the presence of organic materials under various concentrations and exposure/contact time conditions. PMPS could also inactivate NDV and AIV. In addition, PMPS could inactivate AIV on a virus-spiked rayon sheet. In conclusion, the present study showed that PMPS has good antimicrobial properties against SI, E. coli, SI-rif, NDV, and AIV when used at the optimal dosage and exposure timing. These results suggest that PMPS could be used as an alternative disinfectant for biosecurity enhancement in animal farms or hospitals.
评估了一种酸性剂单过硫酸氢钾（PMPS）在有无有机物质存在的情况下，对婴儿沙门氏菌（SI）、大肠杆菌、耐利福平婴儿沙门氏菌（SI-rif）、新城疫病毒（NDV）和禽流感病毒（AIV）的杀菌和杀病毒效果。此外，还检测了其对病毒污染衣物上病毒的灭活活性。在各种浓度以及暴露/接触时间条件下，即使存在有机物质，PMPS也能灭活SI、大肠杆菌和SI-rif。PMPS还能灭活NDV和AIV。此外，PMPS能灭活病毒污染的人造纤维布上的AIV。总之，本研究表明，以最佳剂量和暴露时间使用时，PMPS对SI、大肠杆菌、SI-rif、NDV和AIV具有良好的抗菌性能。这些结果表明，PMPS可作为一种替代消毒剂，用于加强动物养殖场或医院的生物安全。
