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8岁以下儿童寰枢椎不稳单纯经关节螺钉固定的可行性及疗效

Feasibility and outcome of stand-alone trans-articular screw fixation in atlantoaxial instability in children less than 8 years of age.

作者信息

Dutta Shumayou, Kundnani Vishal, Dusad Tarun, Patel Ankit

机构信息

Medical Super-Speciality Hospital, 127, E.M Bypass, Mukundapur, Kolkata, West Bengal, 700099, India.

Bombay Hospital & Medical Research Centre, 12, New Marine Lines, Mumbai, 400020, India.

出版信息

Eur Spine J. 2018 Jun;27(6):1342-1348. doi: 10.1007/s00586-018-5510-7. Epub 2018 Feb 12.

Abstract

PURPOSE

To study the feasibility and outcome of stand-alone trans-articular screw (TAS) fixation for atlantoaxial instability (AAI) in children less than 8 years of age.

METHODS

This prospective study was conducted between 2009 and 2014. Thirteen children suffering from AAI were operated for a TAS fixation. Feasibility of TAS fixation was assessed on CT scan and a screw diameter was chosen based on C2 isthmus diameter. Demographic data collected included the etiology for AAI, age, and sex. Intra-operative data recorded was the duration of surgery, blood loss, vertebral artery injury or any adverse event. Radiological evaluation included pre- and post-operative atlantodens interval (ADI) and space available for cord (SAC) and fusion was evaluated at 3, 6, 12 and 24 months. Statistical analysis was done using SPSS software and statistical significance was set at p < 0.05.

RESULTS

The mean age of the final study group was 6.1 ± 1.5 years, with nine males and four females. Mean isthmus diameter on the left and right side was 3.3 ± 0.3 and 3.2 ± 0.2 mm, respectively. Five patients had an isthmus diameter of < 3.2 mm and a 2.7 mm Herbert screw was used in them and in nine patients, a CCS of 3.2 mm was used. Mean pre- and post-op ADI and SAC improved from 5.5 ± 0.8 to 3.1 ± 0.1 mm, respectively, and 9.8 ± 2.8 to 14 ± 0.6 mm, respectively. Fusion was seen in all patients.

CONCLUSIONS

Stand-alone TAS with morselized allograft is safe, feasible and successful in managing AAI in children below 8 years of age. These slides can be retrieved under Electronic Supplementary Material.

摘要

目的

研究单纯经关节螺钉(TAS)固定治疗8岁以下儿童寰枢椎不稳(AAI)的可行性及疗效。

方法

本前瞻性研究于2009年至2014年进行。13例患有AAI的儿童接受了TAS固定手术。根据CT扫描评估TAS固定的可行性,并根据C2峡部直径选择螺钉直径。收集的人口统计学数据包括AAI的病因、年龄和性别。记录的术中数据包括手术时间、失血量、椎动脉损伤或任何不良事件。影像学评估包括术前和术后寰齿间距(ADI)以及脊髓可用空间(SAC),并在3、6、12和24个月时评估融合情况。使用SPSS软件进行统计分析,统计学显著性设定为p < 0.05。

结果

最终研究组的平均年龄为6.1±1.5岁,其中男性9例,女性4例。左侧和右侧峡部的平均直径分别为3.3±0.3和3.2±0.2毫米。5例患者峡部直径<3.2毫米,使用了2.7毫米的Herbert螺钉,9例患者使用了3.2毫米的CCS螺钉。术前和术后ADI和SAC的平均值分别从5.5±0.8毫米改善至3.1±0.1毫米,以及从9.8±2.8毫米改善至14±0.6毫米。所有患者均可见融合。

结论

单纯TAS联合碎骨同种异体骨在治疗8岁以下儿童AAI方面是安全、可行且成功的。这些幻灯片可在电子补充材料中获取。

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