Department of Pharmacy, School of Chemical Sciences and Pharmacy, Central University of Rajasthan, Ajmer, India.
J Pharm Pharmacol. 2018 Apr;70(4):475-487. doi: 10.1111/jphp.12881. Epub 2018 Feb 13.
Barleria cristata (Family: Acanthaceae), commonly known as Philippine violet, is used in different ethnomedical systems for the treatment of a wide range of ailments. This review aimed to provide a scientific overview of B. cristata with reference to its ethnobotanical aspects, geographical distribution, medicinal uses, phytochemistry and pharmacological activity, and critical analyses research gaps and future research opportunities for investigations on this plant.
Ethnomedical uses of the plant have been observed in lungs disorders, inflammatory conditions, toothache, anaemia, snake bite, diabetes and tuberculosis. The exhaustive bibliographic research carried out on this plant revealed that the plant parts are rich in various phytochemical constituents including triterpenes, phenolic compounds, glycosides and flavonoids type phenolic compounds. Furthermore, the plant was also investigated in terms of its anti-inflammatory, antibacterial, antidiabetic, antifungal, hepatoprotective and antioxidant activity.
This review confirms that B. cristata is a potential herb for the treatment of a wide range of diseases especially lung disorders and inflammatory conditions. Modern pharmacological studies have also validated many ethnobotanical uses of B. cristata, though data regarding many aspects of this plant such as mechanism of action, adverse effects of extracts and active compounds are still limited which call for additional studies.
山靛（爵床科），俗称菲律宾紫罗兰，在不同的民族医学系统中被用于治疗多种疾病。本综述旨在提供关于 B. cristata 的科学概述，包括其民族植物学方面、地理分布、药用用途、植物化学和药理学活性，并对该植物的研究空白和未来研究机会进行批判性分析。
人们观察到该植物在肺部疾病、炎症性疾病、牙痛、贫血、蛇咬伤、糖尿病和肺结核方面的民间用途。对该植物进行的广泛文献研究表明，植物部分富含各种植物化学成分，包括三萜类、酚类化合物、糖苷和类黄酮酚类化合物。此外，该植物还被研究了其抗炎、抗菌、抗糖尿病、抗真菌、保肝和抗氧化活性。
本综述证实 B. cristata 是一种治疗多种疾病的潜在草药，特别是肺部疾病和炎症性疾病。现代药理学研究也验证了 B. cristata 的许多民族植物学用途，尽管关于该植物的许多方面的数据，如作用机制、提取物和活性化合物的不良反应仍然有限，这需要进一步的研究。
