Concentration of ciprofloxacin in human prostatic tissue after oral administration.
作者信息
Dan M, Golomb J, Gorea A, Braf Z, Berger S A
出版信息
Antimicrob Agents Chemother. 1986 Jul;30(1):88-9. doi: 10.1128/AAC.30.1.88.
Abstract
Concomitant concentrations of ciprofloxacin in serum, urine, and prostatic tissue were determined in 15 patients after single oral doses of 750 mg. Levels in tissue ranged from 0.6 to 4.18 micrograms/g, and therapeutic concentrations were demonstrable for up to 9 h after administration. The mean ratio of tissue to serum concentration was 0.93 +/- 0.08 (standard error).
摘要
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