多领域多货物输送载具的发展与挑战。
Advancements and Challenges in Multidomain Multicargo Delivery Vehicles.
机构信息
Regenerative, Modular and Developmental Engineering Laboratory (REMODEL), Biomedical Sciences Building, National University of Ireland Galway (NUI Galway), Ireland.
Science Foundation Ireland (SFI), Centre for Research in Medical Devices (CÚRAM), Biomedical Sciences Building, National University of Ireland Galway (NUI Galway), Ireland.
出版信息
Adv Mater. 2018 Mar;30(13):e1704324. doi: 10.1002/adma.201704324. Epub 2018 Feb 15.
Reparative and regenerative processes are well-orchestrated temporal and spatial events that are governed by multiple cells, molecules, signaling pathways, and interactions thereof. Yet again, currently available implantable devices fail largely to recapitulate nature's complexity and sophistication in this regard. Herein, success stories and challenges in the field of layer-by-layer, composite, self-assembly, and core-shell technologies are discussed for the development of multidomain/multicargo delivery vehicles.
修复和再生过程是经过精心协调的时空事件，受多种细胞、分子、信号通路及其相互作用的控制。然而，目前可用的植入式设备在很大程度上未能再现自然界在这方面的复杂性和复杂性。本文讨论了层层、复合材料、自组装和核壳技术领域在开发多域/多载体药物输送系统方面的成功案例和挑战。
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