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静电纺丝和静电喷雾支架在组织工程中的应用。

Electrospun and Electrosprayed Scaffolds for Tissue Engineering.

机构信息

Hematology and Stem Cell Laboratory, Faculty of Pharmacy and Post Graduate Program in Physiology, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil.

出版信息

Adv Exp Med Biol. 2018;1078:79-100. doi: 10.1007/978-981-13-0950-2_5.

Abstract

Electrospinning and electrospraying technologies provide an accessible and universal synthesis method for the continuous preparation of nanostructured materials. This chapter introduces recent uses of electrospun and electrosprayed scaffolds for tissue regeneration applications. More recent in vitro and in vivo of electrospun fibers are also discussed in relation to soft and hard tissue engineering applications. The focus is made on the bone, vascular, skin, neural and soft tissue regeneration. An introduction is presented regarding the production of biomaterials made by synthetic and natural polymers and inorganic and metallic materials for use in the production of scaffolds for regenerative medicine. For this proposal, the following techniques are discussed: electrospraying, co-axial and emulsion electrospinning and bio-electrospraying. Tissue engineering is an exciting and rapidly developing field for the understanding of how to regenerate the human body.

摘要

静电纺丝和静电喷雾技术为连续制备纳米结构材料提供了一种易于使用且通用的合成方法。本章介绍了静电纺丝和静电喷雾支架在组织再生应用中的最新用途。还讨论了与软、硬组织工程应用相关的更近期的静电纺纤维的体外和体内研究。重点是骨、血管、皮肤、神经和软组织的再生。介绍了用于再生医学支架生产的合成和天然聚合物以及无机和金属材料的生物材料的生产。对于这个建议,讨论了以下技术:静电喷雾、同轴和乳液静电纺丝以及生物静电喷雾。组织工程是一个令人兴奋且快速发展的领域,旨在了解如何再生人体。

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