Department of Epidemiology, Ministry of Health of Chile, Santiago, Chile.
Sub-Department of Viral Diseases, Instituto de Salud Pública de Chile, Santiago, Chile.
Influenza Other Respir Viruses. 2018 Jan;12(1):138-145. doi: 10.1111/irv.12502. Epub 2018 Feb 14.
Influenza is a vaccine preventable disease that causes important morbidity and mortality worldwide. Estimating the burden of influenza disease is difficult. However, there are some methods based in surveillance data and laboratory testing that can be used for this purpose.
Estimating the burden of serious illness from influenza by means of hospitalization and death records during the period between 2012 and 2014, and using information from Severe Acute Respiratory Illness (SARI) surveillance.
To estimate the Chilean rate of influenza-associated hospitalizations and deaths, we applied the influenza positivity of respiratory samples tested in six SARI surveillance sentinel hospitals to the hospitalizations and deaths from the records with ICD-10 codes from influenza and pneumonia.
Annually, 5320 people are hospitalized for influenza and 447 die for this cause. The annual influenza-associated hospitalization rate for the period was 71.5/100 000 person-year for <5 years old, 11.8/100 000 person-year for people between 5 and 64 years old; and 156.0/100 000 person-year for ≥65 years. The annual mortality rate for the period was 0.08/100 000 person-year for <5 years; 0.3/100 000 person-year for people between 5 and 64 years; and 22.8/100 000 person-year for ≥65 years.
This is the first study of influenza burden in Chile. Every year an important quantity of hospitalizations and deaths result from influenza infection. In countries in temperate zones, it is important to know the burden of influenza in order to prepare the health care network and to assess preventive intervention currently in practice and the new ones to implementing.
流感是一种可通过疫苗预防的疾病，在全球范围内可导致严重的发病率和死亡率。评估流感疾病负担具有一定难度。然而，基于监测数据和实验室检测，有一些方法可用于此目的。
通过 2012 年至 2014 年期间的住院和死亡记录，以及严重急性呼吸道感染（SARI）监测信息，估计流感导致的严重疾病负担。
为了估算智利流感相关住院和死亡人数，我们将六家 SARI 监测哨点医院呼吸道样本检测的流感阳性率应用于基于国际疾病分类（ICD-10）编码的流感和肺炎住院和死亡记录。
每年有 5320 人因流感住院，447 人因流感死亡。该时期的流感相关住院率为：<5 岁人群为 71.5/100000 人年，5-64 岁人群为 11.8/100000 人年，≥65 岁人群为 156.0/100000 人年。该时期的死亡率为：<5 岁人群为 0.08/100000 人年，5-64 岁人群为 0.3/100000 人年，≥65 岁人群为 22.8/100000 人年。
这是智利流感负担的首次研究。每年都有大量的住院和死亡与流感感染有关。在温带国家，了解流感的疾病负担非常重要，以便为卫生保健网络做好准备，并评估当前实施的预防干预措施以及新的干预措施。
