Sylvia Kristyn E, Lorenz Tierney K, Heiman Julia R, Demas Gregory E
Department of Biology, Indiana University, Bloomington, IN 47405, USA; Center for the Integrative Study of Animal Behavior, Indiana University, Bloomington, IN 47405, USA.
Center for the Integrative Study of Animal Behavior, Indiana University, Bloomington, IN 47405, USA; Kinsey Institute for Research on Sex, Gender, and Reproduction, Indiana University, Bloomington, IN 47405, USA.
Reprod Biol. 2018 Mar;18(1):132-136. doi: 10.1016/j.repbio.2018.01.011. Epub 2018 Feb 15.
Although research has shown interactions between the reproductive system and energy homeostasis, it is not clear how environmental or behavioral factors may factor into these associations. Here we aimed to determine how changes in reproductive state (i.e., phase of the menstrual cycle) and other behavioral and physiological factors may influence leptin levels in healthy women, as well as how sexual activity may play a role in leptin modulation. We collected serum and saliva from 32 healthy women and measured leptin, estradiol, and progesterone. Participants also completed surveys of demographics, health and sexual behaviors, and physical activity. Leptin was predicted by meals per day and missed meals at both menses and ovulation. However, estradiol and physical activity were stronger predictors of leptin at menses, while sexual activity was a stronger predictor of leptin at ovulation. These findings suggest that predictors of serum leptin, and possibly energy storage and expenditure, vary across the menstrual cycle.
尽管研究表明生殖系统与能量平衡之间存在相互作用，但尚不清楚环境或行为因素如何影响这些关联。在这里，我们旨在确定生殖状态的变化（即月经周期阶段）以及其他行为和生理因素如何影响健康女性的瘦素水平，以及性行为如何在瘦素调节中发挥作用。我们收集了32名健康女性的血清和唾液，并测量了瘦素、雌二醇和孕酮。参与者还完成了关于人口统计学、健康和性行为以及身体活动的调查。每天的进餐次数以及月经和排卵期的漏餐次数可预测瘦素水平。然而，雌二醇和身体活动在月经期间是瘦素的更强预测因素，而性行为在排卵期是瘦素的更强预测因素。这些发现表明，血清瘦素的预测因素，以及可能的能量储存和消耗，在月经周期中各不相同。
