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临床指南中的药物遗传学信息:欧洲视角。

Pharmacogenetic Information in Clinical Guidelines: The European Perspective.

机构信息

Department of Clinical Pharmacy & Toxicology, Leiden University Medical Centre, Leiden, The Netherlands.

Leiden Network for Personalised Therapeutics, Leiden University Medical Centre, Leiden, The Netherlands.

出版信息

Clin Pharmacol Ther. 2018 May;103(5):795-801. doi: 10.1002/cpt.1049. Epub 2018 Mar 30.

DOI:10.1002/cpt.1049
PMID:29460273
Abstract

Surveys among pharmacists and physicians show that these healthcare professionals have successfully adopted the concept of pharmacogenomics (PGx). In addition, patients are willing to consent to participate in PGx implementation studies. However, the surveys also show that healthcare professionals do not frequently order or recommend a PGx test. Among others, a frequently perceived hurdle for clinical uptake of PGx is the availability of guidelines translating PGx test results into clinical actions for individual patients..

摘要

对药剂师和医生的调查表明,这些医疗保健专业人员已经成功地采用了药物基因组学(PGx)的概念。此外,患者也愿意同意参与 PGx 实施研究。然而,调查还表明,医疗保健专业人员并不经常开或推荐 PGx 测试。其中,PGx 临床应用的一个经常被感知到的障碍是缺乏将 PGx 测试结果转化为个体患者临床行动的指南。

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