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分析埃及和黎巴嫩在药物基因组学方面的教育和医疗需求的现状。

Analysis of the current situation of pharmacogenomics in terms of educational and healthcare needs in Egypt and Lebanon.

机构信息

Department of Pharmacology & Toxicology, Faculty of Pharmacy, Alexandria University, Alexandria, 21500, Egypt.

Department of Biochemistry, Faculty of Pharmacy, Alexandria University, Alexandria, 21500, Egypt.

出版信息

Pharmacogenomics. 2024;25(10-11):429-440. doi: 10.1080/14622416.2024.2403967. Epub 2024 Oct 9.

DOI:10.1080/14622416.2024.2403967
PMID:39382016
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11492645/
Abstract

Pharmacogenomics (PGx) is a practice that investigates the link between genetic differences and drug response in patients. This can improve treatment effectiveness and reduce harmful side effects. However, has yet to be adequately realized in developing nations. Three surveys were conducted between November 2022 to March 2023 in Egypt and Lebanon. The first survey assessed availability of PGx testing in different healthcare facilities; the second one assessed knowledge, interest and attitude toward learning about PGx among pharmacists and physicians; and the third one assessed interest in providing PGx education at academic levels. In Egypt, a few of the surveyed healthcare facilities are conducting some form of pharmacogenetic testing. In Lebanon, very few germline pharmacogenomic tests are offered in Greater Beirut's leading hospitals, and no other testing was recorded. PGx education attracts considerable interest, with 34.3% of pharmacists very interested and 48.8% interested. Similarly, 24.8% of total physicians were very interested while 44.8% were interested. Academic professionals in the surveyed institutions in both countries agreed on the need for educational programs in PGx and 78.2% agreed that there were good opportunities for implementing PGx testing. These findings clearly indicate the need to develop and implement educational programs in PGx in the Middle-East.

摘要

药物基因组学(PGx)是一种研究患者遗传差异与药物反应之间关系的实践。这可以提高治疗效果并减少有害的副作用。然而,在发展中国家尚未得到充分实现。2022 年 11 月至 2023 年 3 月,在埃及和黎巴嫩进行了三项调查。第一项调查评估了不同医疗机构中 PGx 检测的可用性;第二项评估了药剂师和医生对学习 PGx 的知识、兴趣和态度;第三项评估了在学术层面提供 PGx 教育的兴趣。在埃及,一些被调查的医疗机构正在进行某种形式的药物遗传学检测。在黎巴嫩,只有少数生殖系药物基因组学测试在贝鲁特的主要医院提供,没有其他测试记录。PGx 教育引起了相当大的兴趣,有 34.3%的药剂师非常感兴趣,48.8%的药剂师感兴趣。同样,24.8%的医生非常感兴趣,而 44.8%的医生感兴趣。两国被调查机构的专业学术人员都认为有必要在 PGx 方面开展教育项目,78.2%的人认为有很好的机会实施 PGx 测试。这些发现清楚地表明,中东地区需要制定和实施 PGx 教育计划。

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本文引用的文献

1
Pharmacogenomics in primary care: a quality improvement project at Alconbury and Brampton surgeries 2019-2023.初级保健中的药物基因组学:2019-2023 年在 Alconbury 和 Brampton 外科的质量改进项目。
Br J Gen Pract. 2024 Jun 20;74(suppl 1):bjgp24X737901. doi: 10.3399/bjgp24X737901.
2
Pharmacogenomics in Lebanon: current status, challenges and opportunities.黎巴嫩的药物基因组学:现状、挑战与机遇
Pharmacogenomics J. 2024 May 22;24(3):16. doi: 10.1038/s41397-024-00336-z.
3
Pharmacogenomics: Driving Personalized Medicine.药物基因组学:推动个性化医疗。
Pharmacol Rev. 2023 Jul;75(4):789-814. doi: 10.1124/pharmrev.122.000810. Epub 2023 Mar 16.
4
A 12-gene pharmacogenetic panel to prevent adverse drug reactions: an open-label, multicentre, controlled, cluster-randomised crossover implementation study.一个 12 基因药物遗传学检测面板以预防药物不良反应:一项开放标签、多中心、对照、集群随机交叉实施研究。
Lancet. 2023 Feb 4;401(10374):347-356. doi: 10.1016/S0140-6736(22)01841-4.
5
An objective evaluation of fundamental pharmacogenomics knowledge among pharmacists and pharmacy students.对药剂师和药学专业学生基本药物基因组学知识的客观评估。
Saudi Pharm J. 2022 Dec;30(12):1765-1772. doi: 10.1016/j.jsps.2022.10.005. Epub 2022 Oct 12.
6
Pharmacogenomics implementation in cardiovascular disease in a highly diverse population: initial findings and lessons learned from a pilot study in United Arab Emirates.在高度多样化的人群中实施心血管疾病的药物基因组学:来自阿拉伯联合酋长国试点研究的初步发现和经验教训。
Hum Genomics. 2022 Sep 25;16(1):42. doi: 10.1186/s40246-022-00417-9.
7
Genomics in Egypt: Current Status and Future Aspects.埃及的基因组学:现状与未来展望
Front Genet. 2022 May 13;13:797465. doi: 10.3389/fgene.2022.797465. eCollection 2022.
8
Demand for Pharmacogenomics and Personalized Medicine in the United Arab Emirates.阿拉伯联合酋长国对药物基因组学和个性化医疗的需求。
J Pers Med. 2022 Jan 14;12(1):104. doi: 10.3390/jpm12010104.
9
The Role of Angiotensin Converting Enzyme 1 Insertion/Deletion Genetic Polymorphism in the Risk and Severity of COVID-19 Infection.血管紧张素转换酶1插入/缺失基因多态性在2019冠状病毒病感染风险及严重程度中的作用
Front Med (Lausanne). 2021 Dec 23;8:798571. doi: 10.3389/fmed.2021.798571. eCollection 2021.
10
Pharmacogenetics: Knowledge assessment amongst Syrian pharmacists and physicians.药物遗传学:叙利亚药剂师和医师的知识评估。
BMC Health Serv Res. 2021 Oct 1;21(1):1031. doi: 10.1186/s12913-021-07040-9.