• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

癌症中的上皮-间质转化

The Epithelial-to-Mesenchymal Transition in Cancer.

作者信息

Roche Joëlle

机构信息

Université de Poitiers, UMR-CNRS 7267, Laboratoire EBI, SEVE, F-86073 Poitiers, France.

出版信息

Cancers (Basel). 2018 Feb 16;10(2):52. doi: 10.3390/cancers10020052.

DOI:10.3390/cancers10020052
PMID:29462906
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5836084/
Abstract

The epithelial-to-mesenchymal transition (EMT) occurs during normal embryonic development, tissue regeneration, organ fibrosis, and wound healing.[...].

摘要

上皮-间质转化（EMT）发生于正常胚胎发育、组织再生、器官纤维化和伤口愈合过程中。[……]

相似文献

1
The Epithelial-to-Mesenchymal Transition in Cancer.癌症中的上皮-间质转化
Cancers (Basel). 2018 Feb 16;10(2):52. doi: 10.3390/cancers10020052.
2
Epithelial-mesenchymal transition in tissue repair and fibrosis.组织修复与纤维化过程中的上皮-间质转化
Cell Tissue Res. 2016 Sep;365(3):495-506. doi: 10.1007/s00441-016-2464-0. Epub 2016 Jul 27.
3
The role of mesenchymal-epithelial transition in endometrial function.间质-上皮转化在子宫内膜功能中的作用。
Hum Reprod Update. 2019 Jan 1;25(1):114-133. doi: 10.1093/humupd/dmy035.
4
Involvement of epithelial-mesenchymal transition in liver fibrosis.上皮-间质转化在肝纤维化中的作用
Saudi J Gastroenterol. 2018 Jan-Feb;24(1):5-11. doi: 10.4103/sjg.SJG_297_17.
5
Signaling pathways promoting epithelial mesenchymal transition in oral submucous fibrosis and oral squamous cell carcinoma.促进口腔黏膜下纤维化和口腔鳞状细胞癌上皮-间质转化的信号通路
Jpn Dent Sci Rev. 2020 Nov;56(1):97-108. doi: 10.1016/j.jdsr.2020.07.002. Epub 2020 Aug 22.
6
Type 2 epithelial mesenchymal transition in vivo: truth or pitfalls?体内 2 型上皮间质转化：真相还是陷阱？
Chin Med J (Engl). 2012 Sep;125(18):3312-7.
7
The epithelial-mesenchymal transition (EMT) is regulated by oncoviruses in cancer.上皮-间质转化（EMT）在癌症中受肿瘤病毒调控。
FASEB J. 2016 Sep;30(9):3001-10. doi: 10.1096/fj.201600388R. Epub 2016 Jun 8.
8
[The epithelial-mesenchymal transition and fibrosis of the renal transplant].肾移植的上皮-间质转化与纤维化
Med Sci (Paris). 2015 Jan;31(1):68-74. doi: 10.1051/medsci/20153101015. Epub 2015 Feb 6.
9
[The role of epithelial-mesenchymal transition in the gastroenterology].上皮-间质转化在胃肠病学中的作用
Korean J Gastroenterol. 2010 Aug;56(2):69-77. doi: 10.4166/kjg.2010.56.2.69.
10
The role of the epithelial-to-mesenchymal transition (EMT) in diseases of the salivary glands.上皮-间充质转化（EMT）在唾液腺疾病中的作用。
Histochem Cell Biol. 2018 Aug;150(2):133-147. doi: 10.1007/s00418-018-1680-y. Epub 2018 May 23.

引用本文的文献

1
A Multi-Layered Framework for Modeling Human Biology: From Basic AI Agents to a Full-Body AI Agent.用于模拟人类生物学的多层框架：从基本人工智能代理到全身人工智能代理。
ArXiv. 2025 Aug 27:arXiv:2508.19800v1.
2
The association between periostin and tumor microenvironment: a promising cancer prognostic biomarker and therapeutic target to combat tumor progression and chemoresistance.骨膜蛋白与肿瘤微环境之间的关联：一种对抗肿瘤进展和化疗耐药性的有前景的癌症预后生物标志物及治疗靶点。
Cancer Cell Int. 2025 Sep 3;25(1):320. doi: 10.1186/s12935-025-03959-9.
3
The Transcription Factor CREB1 Triggers the Progression of Clear Cell Renal Cell Carcinoma by Promoting CENPE Expression.转录因子CREB1通过促进CENPE表达触发透明细胞肾细胞癌进展。
J Cell Mol Med. 2025 Aug;29(15):e70773. doi: 10.1111/jcmm.70773.
4
PAR2 regulates proliferation, migration of lung cancer and chemotherapy sensitivity by involving PTEN pathway.蛋白酶激活受体2（PAR2）通过磷脂酰肌醇-3,4,5-三磷酸酯酶（PTEN）途径调节肺癌的增殖、迁移及化疗敏感性。
Future Sci OA. 2025 Dec;11(1):2535221. doi: 10.1080/20565623.2025.2535221. Epub 2025 Jul 21.
5
Uncovering the molecular signature of feline diffuse iris melanoma through transcriptomic analysis of disease severity.通过对疾病严重程度的转录组分析揭示猫弥漫性虹膜黑色素瘤的分子特征。
Sci Rep. 2025 Jul 19;15(1):26218. doi: 10.1038/s41598-025-09632-5.
6
Elevated SNHG1 promotes invasion and migration of Cd(II)-transformed cells through Sox2, Rac1, and Slug.升高的SNHG1通过Sox2、Rac1和Slug促进镉（II）转化细胞的侵袭和迁移。
Toxicol Appl Pharmacol. 2025 Sep;502:117452. doi: 10.1016/j.taap.2025.117452. Epub 2025 Jun 24.
7
A Potential Oncoprotective Role of Cytomegalovirus Against Breast Cancer: Worldwide Correlation and Survey of Evidence.巨细胞病毒对乳腺癌的潜在肿瘤保护作用：全球相关性及证据调查
Diseases. 2025 Jun 9;13(6):181. doi: 10.3390/diseases13060181.
8
NDRG1 and its family members: More than just metastasis suppressor proteins and targets of thiosemicarbazones.NDRG1及其家族成员：不仅仅是转移抑制蛋白和硫代氨基脲类化合物的靶点。
J Biol Chem. 2025 May 14;301(7):110230. doi: 10.1016/j.jbc.2025.110230.
9
Molecular Mechanisms Regulating Epithelial Mesenchymal Transition (EMT) to Promote Cancer Progression.调控上皮间质转化（EMT）以促进癌症进展的分子机制
Int J Mol Sci. 2025 May 3;26(9):4364. doi: 10.3390/ijms26094364.
10
The relationship between oral burns and oral squamous cell carcinoma: a systematic review.口腔烧伤与口腔鳞状细胞癌之间的关系：一项系统综述。
Ann Med Surg (Lond). 2025 Mar 28;87(5):2896-2903. doi: 10.1097/MS9.0000000000003194. eCollection 2025 May.

本文引用的文献

1
Regulation of EMT in Colorectal Cancer: A Culprit in Metastasis.结直肠癌中上皮-间质转化的调控：转移的罪魁祸首
Cancers (Basel). 2017 Dec 16;9(12):171. doi: 10.3390/cancers9120171.
2
The Epithelial-to-Mesenchymal Transition in Breast Cancer: Focus on Basal-Like Carcinomas.乳腺癌中的上皮-间质转化：聚焦于基底样癌
Cancers (Basel). 2017 Sep 30;9(10):134. doi: 10.3390/cancers9100134.
3
The Emerging Role of Polo-Like Kinase 1 in Epithelial-Mesenchymal Transition and Tumor Metastasis.Polo样激酶1在上皮-间质转化和肿瘤转移中的新作用
Cancers (Basel). 2017 Sep 27;9(10):131. doi: 10.3390/cancers9100131.
4
EMT and Treatment Resistance in Pancreatic Cancer.胰腺癌中的上皮-间质转化与治疗耐药性
Cancers (Basel). 2017 Sep 12;9(9):122. doi: 10.3390/cancers9090122.
5
The Role of Cancer-Derived Exosomes in Tumorigenicity & Epithelial-to-Mesenchymal Transition.癌症衍生外泌体在肿瘤发生及上皮-间质转化中的作用
Cancers (Basel). 2017 Aug 10;9(8):105. doi: 10.3390/cancers9080105.
6
Complex Determinants of Epithelial: Mesenchymal Phenotypic Plasticity in Ovarian Cancer.卵巢癌上皮-间质表型可塑性的复杂决定因素
Cancers (Basel). 2017 Aug 9;9(8):104. doi: 10.3390/cancers9080104.
7
Epithelial-to-Mesenchymal Transition and MicroRNAs in Lung Cancer.肺癌中的上皮-间质转化与微小RNA
Cancers (Basel). 2017 Aug 3;9(8):101. doi: 10.3390/cancers9080101.
8
EMT/MET at the Crossroad of Stemness, Regeneration and Oncogenesis: The Ying-Yang Equilibrium Recapitulated in Cell Spheroids.上皮-间质转化/间质-上皮转化处于干性、再生与肿瘤发生的十字路口：细胞球体中重现的阴阳平衡
Cancers (Basel). 2017 Jul 29;9(8):98. doi: 10.3390/cancers9080098.
9
Epithelial-to-Pericyte Transition in Cancer.癌症中的上皮细胞向周细胞转变
Cancers (Basel). 2017 Jul 4;9(7):77. doi: 10.3390/cancers9070077.
10
Epithelial-mesenchymal transition in cancer.癌症中的上皮-间质转化
Mol Oncol. 2017 Jul;11(7):715-717. doi: 10.1002/1878-0261.12094.