Grecco Henrique A T, Amorim Alessandro B, Saleh Mayra A D, L P Tse Marcos, Telles Filipe G, Miassi Gabriela M, Pimenta Guilherme M, Berto Dirlei A
Departamento de Produção Animal, Faculdade de Medicina Veterinária e Zootecnia, Universidade Estadual Paulista, Botucatu, SP, Brazil.
Instituto de Ciências Agrárias e Tecnológicas, Universidade Federal do Mato Grosso, Rondonópolis, MG, Brazil.
An Acad Bras Cienc. 2018 Feb 19;90(1):401-414. doi: 10.1590/0001-3765201820160057. Print 2018 Jan-Mar.
Two experiments (E) were carried out to evaluate the effects of fumaric acid and an acidifier blend [composed by calcium formate, calcium lactate and medium-chain fatty acids (capric and caprylic)] in piglet diets containing colistin (40 ppm) or halquinol (120 ppm) on performance, diarrhea incidence (E1), organs relative weight, pH values, intestinal morphometry and microbiota (E2). In E1, 192 and E2, 24 piglets weaned at 21-day-old were randomly assigned to blocks with 2x2 factorial arrangement of treatments [absence or presence of fumaric acid x absence or presence of acidifier blend], six replicates of eight (E1) and one piglet per pen (E2). For E1, the treatments were control (CD): no acidifier product + 40 ppm of colistin, FA: fumaric acid in absence of acidifier blend, AB: acidifier blend in absence of fumaric acid and, AF+AB: presence of fumaric acid and acidifier blend. For E2, the pre-starter I diet were used and the same treatments as E1 evaluated. No treatment effects (P>0.05) were observed on performance, diarrhea incidence (E1), gut pH values and duodenum morphometry of piglets (E2). However, the addition of AB increased (P<0.05) large intestine relative weight and, FA addition decreased (P<0.05) pancreas relative weight, jejunum villi height and, total coliform and E. coli counts in cecum. The inclusion of FA and AB in diets containing colistin or halquinol did not improve performance, although FA exerted an inhibitory effect on cecum microbiota.
进行了两项试验（E），以评估富马酸和一种酸化剂混合物[由甲酸钙、乳酸钙和中链脂肪酸（癸酸和辛酸）组成]在含有粘菌素（40 ppm）或卤喹诺（120 ppm）的仔猪日粮中对生产性能、腹泻发生率（E1）、器官相对重量、pH值、肠道形态学和微生物群（E2）的影响。在E1试验中，192头仔猪（E2试验中为24头）在21日龄断奶，被随机分配到各处理组，采用2×2析因设计[富马酸的有无×酸化剂混合物的有无]，E1试验每组8头仔猪，重复6次（E2试验每栏1头仔猪）。对于E1试验，处理组分别为：对照组（CD）：不添加酸化剂产品+40 ppm粘菌素；FA组：不添加酸化剂混合物时添加富马酸；AB组：不添加富马酸时添加酸化剂混合物；AF+AB组：同时添加富马酸和酸化剂混合物。对于E2试验，使用开食前期I日粮，并评估与E1试验相同的处理组。未观察到处理对仔猪生产性能、腹泻发生率（E1）、肠道pH值和十二指肠形态学（E2）有显著影响（P>0.05）。然而，添加AB组增加了（P<0.05）大肠相对重量，添加FA组降低了（P<0.05）胰腺相对重量、空肠绒毛高度以及盲肠中总大肠菌群和大肠杆菌数量。在含有粘菌素或卤喹诺的日粮中添加FA和AB并未改善生产性能，尽管FA对盲肠微生物群有抑制作用。
