He Xiaoxia, Liu Guowu, Xia Dongyan, Feng Xia, Lv Yi, Cheng Huanyi, Wang Yuehua, Lu Hongyan, Jiang Yan
National HIV/HCV Reference Laboratory, National Center for AIDS/STD Control and Prevention, China CDC, Beijing, China.
Beijing Center for Disease Control and Prevention, Beijing, China.
PLoS One. 2018 Feb 22;13(2):e0192255. doi: 10.1371/journal.pone.0192255. eCollection 2018.
Innovative human immunodeficiency virus (HIV) testing services will be needed to achieve the first 90 (90% of HIV-positive persons aware of their infection status) of the 90-90-90 target in China. Here, we describe an internet-based urine delivery testing service delivered through three pilot drugstores in Beijing that send specimens to a designated laboratory for HIV. From May 2016 to January 2017, we provided 500 HIV urine-testing service packs for display at the drugstores, and a total of 430 (86.0%) urine specimens were mailed back. All of the 430 urine specimens were of good quality and were tested. 70 urine specimens were HIV positive, showing a 16.3% (70/430) positivity rate. A total of 94.3% (66/70) of the HIV-positive participants obtained their test results through the internet, and 69.7% (46/66) of these participants received follow-up care. A total of 40 out of 46 (87.0%) participants agreed to have their results confirmed by a blood test, and 39 out of 40 (97.5%) participants were confirmed as HIV-1 positive, including two individuals that were previously diagnosed. Lastly, 28 out of 37 (75.7%) of the study participants were referred to the hospital and provided free antiviral treatment. Our data indicate that this innovative HIV testing service is effective and play an important role in HIV testing and surveillance.
在中国,需要创新的人类免疫缺陷病毒(HIV)检测服务,以实现90-90-90目标中的第一个90(90%的HIV阳性者知晓自己的感染状况)。在此,我们描述一项通过北京的三家试点药店提供的基于互联网的尿液送检检测服务,这些药店将样本送至指定的HIV实验室。2016年5月至2017年1月,我们提供了500个HIV尿液检测服务包在药店展示,共有430份(86.0%)尿液样本被寄回。所有430份尿液样本质量良好并进行了检测。70份尿液样本HIV呈阳性,阳性率为16.3%(70/430)。共有94.3%(66/70)的HIV阳性参与者通过互联网获取了检测结果,其中69.7%(46/66)的参与者接受了后续护理。46名参与者中有40名(87.0%)同意通过血液检测确认结果,40名参与者中有39名(97.5%)被确认为HIV-1阳性,其中包括两名先前已被诊断的个体。最后,37名研究参与者中有28名(75.7%)被转诊至医院并接受了免费抗病毒治疗。我们的数据表明,这项创新的HIV检测服务是有效的,在HIV检测和监测中发挥着重要作用。