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后路腰椎椎间融合术在最小化椎间盘撑开情况下相邻节段疾病发生率低:初步报告

Low incidence of adjacent segment disease after posterior lumbar interbody fusion with minimum disc distraction: A preliminary report.

作者信息

Makino Takahiro, Honda Hirotsugu, Fujiwara Hiroyasu, Yoshikawa Hideki, Yonenobu Kazuo, Kaito Takashi

机构信息

Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, Suita Department of Orthopedic Surgery, Japan Community Health care Organization Hoshigaoka Medical Center, Hirakata Department of Orthopedic Surgery, National Hospital Organization Osaka Minami Medical Center, Kawachinagano Osaka Yukioka Medical University, Ibaraki, Japan.

出版信息

Medicine (Baltimore). 2018 Jan;97(2):e9631. doi: 10.1097/MD.0000000000009631.

Abstract

STUDY DESIGN

A retrospective review of prospectively collected data.

OBJECTIVE

To investigate the incidence of radiographic and symptomatic adjacent segment disease (ASD) and identify possible risk factors for ASD after posterior lumbar interbody fusion (PLIF) with minimum disc distraction by selecting low-height interbody cages.

SUMMARY OF BACKGROUND DATA

Excessive disc space distraction is reportedly 1 of the risk factors for ASD after PLIF; however, the incidence and other risk factors of ASD after PLIF with minimum disc distraction remain unclear.

METHODS

Forty-one consecutive patients who underwent PLIF at L4-L5 and were postoperatively followed up for a minimum of 2 years were included. The height and shape (box or bullet shape) of interbody cages was determined according to the disc height and morphology of the intervertebral space assessed on preoperative computed tomography scans to avoid excessive distraction. The incidence of radiographic and symptomatic ASD was evaluated and all demographic and radiographic parameters were compared between patients with and without ASD. Multivariate logistic regression analysis was performed to identify risk factors for ASD among the variables with P < .20 in univariate analysis.

RESULTS

The overall incidence of ASD was 12.2% (5/41 patients): radiographic ASD, 7.3% (3 patients); symptomatic ASD, 4.9% (2 patients). Multivariate analysis revealed preoperative retrolisthesis of L3 on extension as the sole risk factor for ASD after PLIF with minimum disc distraction (odds ratio, 2.13; 95% confidence interval, 1.00-4.05; P = .049).

CONCLUSIONS

The incidence of ASD in this study was lower than that of ASD in our previous study about PLIF with distraction of disc space (12.2% vs. 31.8%). Minimum disc distraction by selection of low-height interbody cages is a simple and effective method to prevent ASD at the surgeons' discretion, although preexisting retrolisthesis at the adjacent upper segment should be taken into consideration.

摘要

研究设计

对前瞻性收集的数据进行回顾性分析。

目的

通过选择低高度椎间融合器以最小限度撑开椎间盘,调查影像学及有症状的相邻节段疾病(ASD)的发生率,并确定腰椎后路椎间融合术(PLIF)后ASD的可能危险因素。

背景数据总结

据报道,椎间盘间隙过度撑开是PLIF术后ASD的危险因素之一;然而,最小限度撑开椎间盘的PLIF术后ASD的发生率及其他危险因素仍不明确。

方法

纳入41例连续在L4-L5节段接受PLIF且术后至少随访2年的患者。根据术前计算机断层扫描评估的椎间盘高度和椎间隙形态确定椎间融合器的高度和形状(盒形或子弹形),以避免过度撑开。评估影像学及有症状的ASD的发生率,并比较有和没有ASD的患者之间的所有人口统计学和影像学参数。对单因素分析中P<0.20的变量进行多因素逻辑回归分析,以确定ASD的危险因素。

结果

ASD的总体发生率为12.2%(5/41例患者):影像学ASD为7.3%(3例患者);有症状的ASD为4.9%(2例患者)。多因素分析显示,在最小限度撑开椎间盘的PLIF术后,L3节段后伸位椎体滑脱是ASD的唯一危险因素(比值比,2.13;95%置信区间,1.00-4.05;P=0.049)。

结论

本研究中ASD的发生率低于我们之前关于撑开椎间盘间隙的PLIF研究中的发生率(12.2%对31.8%)。选择低高度椎间融合器以最小限度撑开椎间盘是一种简单有效的方法,可由外科医生酌情预防ASD,尽管应考虑相邻上段先前存在的椎体滑脱情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c2e/5943881/2c59b805191e/medi-97-e9631-g001.jpg

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