Raut Ashwinikumar A, Vaidya Ashok D B
Clinical Research and Integrative Medicine, MRC-KHS, K. Desai Road, Vile Parle (W), Mumbai 400056, Maharashtra, India.
Medical Research Centre, Kasturba Health Society, Vile Parle (W), Mumbai 400056, Maharashtra, India.
J Ayurveda Integr Med. 2018 Jan-Mar;9(1):64-66. doi: 10.1016/j.jaim.2017.12.005. Epub 2018 Feb 24.
For millennia, cow has been central to Indian economy, life and culture. There are innumerable references-Vedic and subsequent to the sacred significance of cow. The benefits of cow have been described at length in relation to agriculture, environment, health, economy and spiritual progress. However, the socio-political issues surrounding cow as a sacred animal have raised acrimonious debates. In Ayurveda also, there is a long tradition of using cow products for positive health, pharmaceutical processes and in therapeutics. There have been quite a few studies on the activity, efficacy, safety and acceptability of Panchagavya and other cow products. Paradoxically, many cow products available in the market for human consumption require improved standardization and proper regulation. Integration of cowpathy (Govaidyak) in traditional Indian systems of medicine has been natural, based on their common dravyagunavigyan. But if its integration with conventional medicine is contemplated, we will need better understanding of the ingredients of cow products, their pharmacokinetics, pharmacodynamics and therapeutic ratio. A rational beginning can be made by data collection of experiential and anecdotal responses. A meticulous analysis of database of panchgavya and other cow products should look for temporal relationships, biological plausibility and translational potential before embarking on state-of-the-art experimental and clinical studies for selected indications.
数千年来,牛在印度的经济、生活和文化中一直占据核心地位。吠陀经及后续文献中对牛的神圣意义有着无数记载。牛在农业、环境、健康、经济和精神进步等方面的益处也有详尽描述。然而,围绕牛作为神圣动物的社会政治问题引发了激烈辩论。在阿育吠陀医学中,使用牛产品促进健康、用于制药过程及治疗也有着悠久传统。针对五灵脂及其他牛产品的活性、功效、安全性和可接受性已有不少研究。矛盾的是,市场上许多供人类食用的牛产品需要改进标准化并进行适当监管。基于共同的药物属性知识,牛疗法(Govaidyak)融入印度传统医学体系是自然而然的。但如果考虑将其与传统医学整合,我们需要更好地了解牛产品的成分、药代动力学、药效动力学和治疗比率。可以通过收集经验性和传闻性反应的数据来开启理性的开端。在针对选定适应症开展前沿实验和临床研究之前,对五灵脂及其他牛产品的数据库进行细致分析时,应寻找时间关系、生物学合理性及转化潜力。