黑磷纳米片用于快速 microRNA 检测。

Black phosphorus nanosheets for rapid microRNA detection.

机构信息

Key Laboratory of Optoelectronics Devices and Systems of Ministry of Education/Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen 518060, China.

出版信息

Nanoscale. 2018 Mar 15;10(11):5060-5064. doi: 10.1039/c7nr08900g.

DOI:10.1039/c7nr08900g

PMID:29488527

Abstract

Herein, for the first time, a sensitive sensing platform for rapid detection of microRNA was developed by employing black phosphorus nanosheets as the fluorescence quenching material. The biosensor displayed a good linear response to microRNA ranging from 10 nM to 1000 nM. Moreover, the biosensor could distinguish triple nucleotide polymorphism.

摘要

本文首次开发了一种基于黑磷纳米片作为荧光猝灭材料的灵敏 miRNA 快速检测传感平台。该生物传感器对 10 nM 至 1000 nM 范围内的 microRNA 表现出良好的线性响应。此外，该生物传感器还能够区分三核苷酸多态性。