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通过mRNA重编程产生人诱导多能干细胞系。

Generation of a human iPSC line by mRNA reprogramming.

作者信息

Artero Castro Ana, León Marian, Del Buey Furió Verónica, Erceg Slaven, Lukovic Dunja

机构信息

National Stem Cell Bank-Valencia Node, Biomolecular and Bioinformatics Resources Platform PRB2, ISCIII, Research Centre Principe Felipe, c/Eduardo Primo Yúfera 3, 46012, Valencia, Spain.

National Stem Cell Bank-Valencia Node, Biomolecular and Bioinformatics Resources Platform PRB2, ISCIII, Research Centre Principe Felipe, c/Eduardo Primo Yúfera 3, 46012, Valencia, Spain; Stem Cells Therapies in Neurodegenerative Diseases Lab, Research Center Principe Felipe, c/Eduardo Primo Yufera 3, Valencia 46012, Spain.

出版信息

Stem Cell Res. 2018 Apr;28:157-160. doi: 10.1016/j.scr.2018.02.011. Epub 2018 Feb 20.

DOI:10.1016/j.scr.2018.02.011
PMID:29499498
Abstract

The human iPSC cell line, derived from foreskin fibroblasts was generated by non-integrative, non-viral reprogramming technology using OCT4, SOX2, KLF4, LIN28, c-MYC mRNAs.

摘要

该人诱导多能干细胞系源自包皮成纤维细胞，是采用OCT4、SOX2、KLF4、LIN28、c-MYC信使核糖核酸，通过非整合、非病毒重编程技术生成的。

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