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14 岁前偶发和复发的非自杀性自伤与 17 岁时精神障碍发病的前瞻性队列研究。

Sporadic and recurrent non-suicidal self-injury before age 14 and incident onset of psychiatric disorders by 17 years: prospective cohort study.

机构信息

University of Cambridge and Cambridgeshire and Peterborough NHS Foundation Trust,Cambridge,UK.

University of Cambridge, Cambridge, UK and University of British Columbia,Vancouver,Canada.

出版信息

Br J Psychiatry. 2018 Apr;212(4):222-226. doi: 10.1192/bjp.2017.45. Epub 2018 Mar 8.

Abstract

BACKGROUND

Non-suicidal self-injury (NSSI) is highly prevalent in adolescents and may be a behavioural marker for emergent mental illnesses. Aims To determine whether sporadic or recurrent NSSI up to the age of 14 years predicted increased risk of new onset of psychiatric disorder in the subsequent 3 years, independent of psychiatric symptoms and social risk factors.

METHOD

In total, 945 individuals aged 14 years with no past/present history of mental illness completed a clinical interview and completed a questionnaire about NSSI at the ages of 14 and 17 years.

RESULTS

Recurrent NSSI at baseline predicted total disorders, depression and eating disorders. Sporadic baseline NSSI predicted new onset of anxiety disorders only.

CONCLUSIONS

NSSI (especially recurrent NSSI) in the early-adolescent years is a behavioural marker of newly emerging mental illnesses. Professionals should treat both recurrent and sporadic NSSI as important risk factors, and prevention strategies could be targeted at this vulnerable group. Declaration of interest None.

摘要

背景

非自杀性自伤(NSSI)在青少年中非常普遍,可能是精神疾病早期出现的行为标志物。目的:确定 14 岁之前偶尔或反复发生的 NSSI 是否会增加随后 3 年内新出现精神障碍的风险,而不考虑精神症状和社会风险因素。方法:共有 945 名年龄在 14 岁且没有过去/现在精神病史的个体在 14 岁和 17 岁时完成了临床访谈,并完成了关于 NSSI 的问卷。结果:基线时反复发生的 NSSI 预测了总疾病、抑郁和饮食障碍。基线时偶尔发生的 NSSI 仅预测新出现的焦虑障碍。结论:青少年早期的 NSSI(尤其是反复发生的 NSSI)是新出现精神疾病的行为标志物。专业人员应将反复发生和偶尔发生的 NSSI 都视为重要的风险因素,预防策略可以针对这一脆弱群体。无利益声明。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/950b/7557859/1eb2b573b445/S0007125017000459_fig1.jpg

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