Department of Urology, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju, Korea.
Department of Urology, Gangnam Severance Hospital, Urological Science Institute, Yonsei University College of Medicine, Seoul, Korea.
Investig Clin Urol. 2018 Mar;59(2):112-118. doi: 10.4111/icu.2018.59.2.112. Epub 2018 Feb 1.
This study aims to assess the predictive factors and treatment outcomes of Steinstrasse formation following shock wave lithotripsy (SWL) for ureter stone.
The medical records of 1,418 ureter stone patients who underwent one-session SWL from November 2005 to May 2013 at our medical institute were retrospectively reviewed. Finally, 551 patients met inclusion criteria. Maximal length and location of stone, stone attenuation (Hounsfield units), and skin-to-stone distance (SSD) were determined on pretreatment non-contrast computed tomography.
Of 551 patients, 12 patients (2.2% of total cohort) developed Steinstrasse after one-session SWL. The Steinstrasse incidence was significantly associated with stone size, stone attenuation value, and SSD. Prophylactic ureter stenting was not a statistically significant predictor of Steinstrasse formation. After propensity-score matching, Steinstrasse group showed a significant shorter SSD compare to non-Steinstrasse group. Multivariate logistic regression and Bayesian analysis revealed that stone size, stone attenuation and SSD were significant predictor of Steinstrasse formation following SWL for ureter stone. The Steinstrasse resolved spontaneously in six patients and remaining six patients were treated by additional SWL. None of patients with Steinstrasse required ureteral stenting, percutaneous drainage, or consequent surgical intervention.
Steinstrasse formation following SWL for ureter stone was rare event but nonnegligible. Large stone size, high stone attenuation and short SSD were significant predictors of Steinstrasse formation following SWL for ureter stone. Majority of patients with Steinstrasse formation could be treated conservatively in this clinical scenario.
本研究旨在评估冲击波碎石术(SWL)治疗输尿管结石后 Steinstrasse 形成的预测因素和治疗结果。
回顾性分析 2005 年 11 月至 2013 年 5 月在我院行单次 SWL 的 1418 例输尿管结石患者的病历资料,最终纳入 551 例符合标准的患者。在术前非增强 CT 上确定结石的最大长度和位置、结石衰减值(Hounsfield 单位)和皮肤至结石距离(SSD)。
在 551 例患者中,12 例(占总队列的 2.2%)在单次 SWL 后发生 Steinstrasse。Steinstrasse 的发生率与结石大小、结石衰减值和 SSD 显著相关。预防性输尿管支架置入术不是 Steinstrasse 形成的统计学显著预测因素。经过倾向评分匹配后,Steinstrasse 组的 SSD 明显短于非 Steinstrasse 组。多变量逻辑回归和贝叶斯分析显示,结石大小、结石衰减和 SSD 是 SWL 治疗输尿管结石后 Steinstrasse 形成的显著预测因素。6 例 Steinstrasse 自发缓解,其余 6 例患者接受了额外的 SWL 治疗。没有 Steinstrasse 的患者需要输尿管支架置入、经皮引流或随后的手术干预。
SWL 治疗输尿管结石后 Steinstrasse 形成是罕见但不可忽视的事件。结石较大、衰减值较高和 SSD 较短是 SWL 治疗输尿管结石后 Steinstrasse 形成的显著预测因素。在这种临床情况下,大多数 Steinstrasse 形成的患者可以保守治疗。