Choi Ji Woong, Song Phil Hyun, Kim Hyun Tae
Department of Urology, Yeungnam University College of Medicine, Daegu, Korea.
Korean J Urol. 2012 Jun;53(6):424-30. doi: 10.4111/kju.2012.53.6.424. Epub 2012 Jun 19.
Extracorporeal Shock Wave Lithotripsy (ESWL) has shown successful outcomes for ureteral stones. We investigated predictive factors for failure of ESWL for treating ureteral stones.
A total of 153 patients who underwent ESWL between July 2006 and July 2009 for ureteral stones diagnosed by non-enhanced spiral computed tomography were divided into two groups: (group A, stone size ≤10 mm; and group B, stone size >10 mm). The failure was defined as remnant stones >4 mm. We assessed age, sex, body mass index, stone size, laterality, location, skin-to-stone distance (SSD), Hounsfield unit, and the presence of secondary signs (hydronephrosis, renal enlargement, perinephric fat stranding, and tissue rim sign). We analyzed predictive factors by using logistic regression in each group.
The success rates were 90.2% and 68.6% in group A and B, respectively. In the univariate analysis of each group, stone size, SSD, and all secondary signs showed statistically significant differences in terms of the outcome of ESWL (p<0.05). In the multivariate logistic regression, stone size (odds ratio [OR], 50.005; 95% confidence interval [CI], 6.207 to 402.852) was an independent predictive factor in group A. The presence of perinephric fat standing (OR, 77.634; 95% CI, 1.349 to 446.558) and stone size (OR, 19.718; 95% CI, 1.600 to 243.005) were independent predictive factors in group B.
Stone size is an independent predictive factor influencing failure of ESWL for treating ureteral stones. In larger ureteral stones (>10 mm), the presence of perinephric fat stranding is also an independent predictive factor.
体外冲击波碎石术(ESWL)已显示出治疗输尿管结石的成功效果。我们研究了ESWL治疗输尿管结石失败的预测因素。
对2006年7月至2009年7月期间因非增强螺旋计算机断层扫描诊断为输尿管结石而接受ESWL治疗的153例患者进行分组:(A组,结石大小≤10mm;B组,结石大小>10mm)。失败定义为残余结石>4mm。我们评估了年龄、性别、体重指数、结石大小、侧别、位置、皮肤至结石距离(SSD)、亨氏单位以及是否存在继发性征象(肾积水、肾增大、肾周脂肪条索状影和组织边缘征)。我们在每组中使用逻辑回归分析预测因素。
A组和B组的成功率分别为90.2%和68.6%。在每组的单因素分析中,结石大小、SSD以及所有继发性征象在ESWL治疗结果方面显示出统计学显著差异(p<0.05)。在多因素逻辑回归中,结石大小(比值比[OR],50.005;95%置信区间[CI],6.207至402.852)是A组的独立预测因素。肾周脂肪条索状影的存在(OR,77.634;95%CI,1.349至446.558)和结石大小(OR,19.718;95%CI,1.600至243.005)是B组的独立预测因素。
结石大小是影响ESWL治疗输尿管结石失败的独立预测因素。在较大的输尿管结石(>10mm)中,肾周脂肪条索状影的存在也是一个独立预测因素。