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[细胞死亡的类型]

[Types of cell death].

作者信息

Paduch Roman, Klatka Maria, Klatka Janusz

出版信息

Pomeranian J Life Sci. 2015;61(4):411-8.

PMID:29522663
Abstract

Homeostasis in the body is maintained by multiple processes, including the balance between the formation of new cells and their dying. This paper describes the mechanism and pathways of apoptotic cell death, and the phenomenon of necrosis and autophagy. Furthermore, it describes rarely presented types of cell death, namely mitotic catastrophe, oncosis and pyroptosis. The course of these processes varies, as emphasized in the paper, and is on the one hand connected with maintaining the stability of tissues in physiological processes, but on the other hand processes of cell death are connected with the induction and progression of pathological processes. In the paper an attempt was made to show the basic differences between the described processes and their importance for the body.

摘要

体内的稳态由多种过程维持,包括新细胞形成与细胞死亡之间的平衡。本文描述了凋亡性细胞死亡的机制和途径,以及坏死和自噬现象。此外,还描述了很少出现的细胞死亡类型,即有丝分裂灾难、胀亡和焦亡。如本文所强调的,这些过程的进程各不相同,一方面与维持生理过程中组织的稳定性有关,但另一方面细胞死亡过程与病理过程的诱导和进展有关。本文试图展示所描述过程之间的基本差异及其对身体的重要性。

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