Zhang Lei, Xu Jian
Department of Rheumatology and Immunology, Shengli Oilfield Central HospitalDongying 257034, Shandong, China.
Am J Clin Exp Immunol. 2018 Feb 5;7(1):1-7. eCollection 2018.
Posterior reversible encephalopathy syndrome (PRES) is a rare clinical entity associated with systemic lupus erythematosus which characterized by seizure, headache, and altered mental status. The pathophysiology involves subcortical vasogenic edema secondary to hypertension and endothelial damage. PRES is reversible with withdrawal of the offending agent, strict blood pressure control, and treating the underlying disease. We report present here a patient with lupus nephritis who developed PRES following mycophenolate administration.
后部可逆性脑病综合征（PRES）是一种与系统性红斑狼疮相关的罕见临床病症，其特征为癫痫发作、头痛和精神状态改变。病理生理学涉及继发于高血压和内皮损伤的皮质下血管源性水肿。停用致病因素、严格控制血压并治疗基础疾病后，PRES是可逆的。我们在此报告一名狼疮性肾炎患者，在服用霉酚酸酯后发生了PRES。
