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Antibody-Based Agents in the Management of Antibiotic-Resistant Staphylococcus aureus Diseases.基于抗体的药物在耐抗生素金黄色葡萄球菌疾病管理中的应用
Microorganisms. 2018 Mar 13;6(1):25. doi: 10.3390/microorganisms6010025.
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Monoclonal Antibodies Targeting Surface-Exposed and Secreted Proteins from Staphylococci.靶向葡萄球菌表面暴露蛋白和分泌蛋白的单克隆抗体。
Vaccines (Basel). 2021 May 4;9(5):459. doi: 10.3390/vaccines9050459.
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Protection against Staphylococcus aureus Colonization and Infection by B- and T-Cell-Mediated Mechanisms.通过 B 细胞和 T 细胞介导的机制预防金黄色葡萄球菌定植和感染。
mBio. 2018 Oct 16;9(5):e01949-18. doi: 10.1128/mBio.01949-18.
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Targeting Alpha Toxin and ClfA with a Multimechanistic Monoclonal-Antibody-Based Approach for Prophylaxis of Serious Staphylococcus aureus Disease.采用基于多机制单克隆抗体的方法靶向α毒素和ClfA预防严重金黄色葡萄球菌疾病
mBio. 2016 Jun 28;7(3):e00528-16. doi: 10.1128/mBio.00528-16.
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Targeting Alpha Toxin To Mitigate Its Lethal Toxicity in Ferret and Rabbit Models of Staphylococcus aureus Necrotizing Pneumonia.靶向α毒素以减轻其在金黄色葡萄球菌坏死性肺炎雪貂和兔模型中的致死毒性。
Antimicrob Agents Chemother. 2017 Mar 24;61(4). doi: 10.1128/AAC.02456-16. Print 2017 Apr.
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Protective Efficacy and Mechanism of Passive Immunization with Polyclonal Antibodies in a Sepsis Model of Staphylococcus aureus Infection.多克隆抗体被动免疫在金黄色葡萄球菌感染脓毒症模型中的保护作用及机制
Sci Rep. 2015 Oct 22;5:15553. doi: 10.1038/srep15553.
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A human monoclonal antibody targeting the conserved staphylococcal antigen IsaA protects mice against Staphylococcus aureus bacteremia.一种靶向保守葡萄球菌抗原IsaA的人源单克隆抗体可保护小鼠免受金黄色葡萄球菌菌血症的侵害。
Int J Med Microbiol. 2015 Jan;305(1):55-64. doi: 10.1016/j.ijmm.2014.11.002. Epub 2014 Nov 11.
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Improved Protection in a Rabbit Model of Community-Associated Methicillin-Resistant Staphylococcus aureus Necrotizing Pneumonia upon Neutralization of Leukocidins in Addition to Alpha-Hemolysin.在社区获得性耐甲氧西林金黄色葡萄球菌坏死性肺炎兔模型中，除α-溶血素外，中和杀白细胞素后保护作用增强。
Antimicrob Agents Chemother. 2016 Sep 23;60(10):6333-40. doi: 10.1128/AAC.01213-16. Print 2016 Oct.
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Preclinical Efficacy of Clumping Factor A in Prevention of Staphylococcus aureus Infection.聚集因子A预防金黄色葡萄球菌感染的临床前疗效
mBio. 2016 Feb 2;7(1):e02232-15. doi: 10.1128/mBio.02232-15.
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A natural human monoclonal antibody targeting Staphylococcus Protein A protects against Staphylococcus aureus bacteremia.一种靶向葡萄球菌蛋白A的天然人单克隆抗体可预防金黄色葡萄球菌菌血症。
PLoS One. 2018 Jan 24;13(1):e0190537. doi: 10.1371/journal.pone.0190537. eCollection 2018.
引用本文的文献
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Multi-Omics Analysis of the virulence factors and designing of next-generation multi-epitopes Vaccines against Rickettsia prowazekii: a computer-aided vaccine designing approach.普氏立克次体毒力因子的多组学分析及下一代多表位疫苗设计：一种计算机辅助疫苗设计方法
J Comput Aided Mol Des. 2025 May 26;39(1):25. doi: 10.1007/s10822-025-00603-6.
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Phage display for the detection, analysis, disinfection, and prevention of .用于检测、分析、消毒和预防……的噬菌体展示技术 。（原文结尾不完整，推测可能是某种疾病或其他相关事物）
Smart Med. 2022 Dec 23;1(1):e20220015. doi: 10.1002/SMMD.20220015. eCollection 2022 Dec.
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Advances in the targeted theragnostics of osteomyelitis caused by Staphylococcus aureus.金黄色葡萄球菌引起的骨髓炎的靶向治疗学进展。
Arch Microbiol. 2024 Jun 5;206(7):288. doi: 10.1007/s00203-024-04015-2.
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Methicillin-Resistant Staphylococcus aureus Hospital-Acquired Pneumonia/Ventilator-Associated Pneumonia.耐甲氧西林金黄色葡萄球菌医院获得性肺炎/呼吸机相关性肺炎。
Semin Respir Crit Care Med. 2022 Apr;43(2):304-309. doi: 10.1055/s-0041-1740583. Epub 2022 Feb 15.
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Bactericidal fully human single-chain fragment variable antibodies protect mice against methicillin-resistant bacteraemia.杀菌性全人源单链可变片段抗体可保护小鼠免受耐甲氧西林菌血症的侵害。
Clin Transl Immunology. 2021 Jun 29;10(7):e1302. doi: 10.1002/cti2.1302. eCollection 2021.
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Immunogenomics guided design of immunomodulatory multi-epitope subunit vaccine against the SARS-CoV-2 new variants, and its validation through in silico cloning and immune simulation.基于免疫基因组学设计针对 SARS-CoV-2 新变体的免疫调节多表位亚单位疫苗，并通过计算机模拟克隆和免疫模拟进行验证。
Comput Biol Med. 2021 Jun;133:104420. doi: 10.1016/j.compbiomed.2021.104420. Epub 2021 Apr 24.
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Native Human Antibody to Shr Promotes Mice Survival After Intraperitoneal Challenge With Invasive Group A Streptococcus.天然人源抗链球菌溶血素 Shr 抗体可促进侵袭性 A 组链球菌腹腔感染小鼠的存活
J Infect Dis. 2021 Apr 23;223(8):1367-1375. doi: 10.1093/infdis/jiaa540.
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Human Gene-Encoded Human Monoclonal Antibodies against Staphylococcus aureus IsdB Use at Least Three Distinct Modes of Binding To Inhibit Bacterial Growth and Pathogenesis.人源基因编码的抗金黄色葡萄球菌 IsdB 的人源单克隆抗体至少采用三种不同的结合模式抑制细菌生长和发病机制。
mBio. 2019 Oct 22;10(5):e02473-19. doi: 10.1128/mBio.02473-19.
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Monoclonal antibody-based therapies for bacterial infections.基于单克隆抗体的细菌性感染治疗方法。
Curr Opin Infect Dis. 2019 Jun;32(3):210-216. doi: 10.1097/QCO.0000000000000539.
本文引用的文献
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Passive immunization against methicillin resistant Staphylococcus aureus recombinant PBP2a in sepsis model of mice: Comparable results with antibiotic therapy.在耐甲氧西林金黄色葡萄球菌重组 PBP2a 败血症模型的小鼠中进行的被动免疫：与抗生素治疗具有相当的结果。
Int Immunopharmacol. 2018 Mar;56:186-192. doi: 10.1016/j.intimp.2018.01.035. Epub 2018 Feb 3.
2
A natural human monoclonal antibody targeting Staphylococcus Protein A protects against Staphylococcus aureus bacteremia.一种靶向葡萄球菌蛋白A的天然人单克隆抗体可预防金黄色葡萄球菌菌血症。
PLoS One. 2018 Jan 24;13(1):e0190537. doi: 10.1371/journal.pone.0190537. eCollection 2018.
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Prevalence of IgG and Neutralizing Antibodies against Staphylococcus aureus Alpha-Toxin in Healthy Human Subjects and Diverse Patient Populations.健康人体和不同患者人群中针对金黄色葡萄球菌α-毒素的 IgG 和中和抗体的流行率。
Infect Immun. 2018 Feb 20;86(3). doi: 10.1128/IAI.00671-17. Print 2018 Mar.
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Staphylococcus aureus and Atopic Dermatitis: A Complex and Evolving Relationship.金黄色葡萄球菌与特应性皮炎：复杂且不断变化的关系。
Trends Microbiol. 2018 Jun;26(6):484-497. doi: 10.1016/j.tim.2017.11.008. Epub 2017 Dec 9.
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Inside job: Staphylococcus aureus host-pathogen interactions.内奸：金黄色葡萄球菌与宿主的相互作用。
Int J Med Microbiol. 2018 Aug;308(6):607-624. doi: 10.1016/j.ijmm.2017.11.009. Epub 2017 Nov 26.
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Humoral immune consequences of Staphylococcus aureus ST239-associated bacteremia.金黄色葡萄球菌 ST239 相关性菌血症的体液免疫后果。
Eur J Clin Microbiol Infect Dis. 2018 Feb;37(2):255-263. doi: 10.1007/s10096-017-3124-3. Epub 2017 Nov 4.
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Three-dimensional structures of Lipoproteins from Streptococcus pneumoniae and Staphylococcus aureus.肺炎链球菌和金黄色葡萄球菌脂蛋白的三维结构。
Int J Med Microbiol. 2018 Aug;308(6):692-704. doi: 10.1016/j.ijmm.2017.10.003. Epub 2017 Oct 27.
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Production and Characterization of F(Ab') Fragments Obtained by Enzymatic Digestion from Murine Anti-MRSA PBP2a Monoclonal Antibodies.通过酶解从抗耐甲氧西林金黄色葡萄球菌 PBP2a 单克隆抗体的鼠源性 F(ab') 片段的生产和特性。
Appl Biochem Biotechnol. 2018 May;185(1):72-80. doi: 10.1007/s12010-017-2624-z. Epub 2017 Oct 30.
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The commensal lifestyle of Staphylococcus aureus and its interactions with the nasal microbiota.金黄色葡萄球菌的共生生活方式及其与鼻腔微生物群的相互作用。
Nat Rev Microbiol. 2017 Oct 12;15(11):675-687. doi: 10.1038/nrmicro.2017.104.
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Differential epitope recognition in the immunodominant staphylococcal antigen A of Staphylococcus aureus by mouse versus human IgG antibodies.金黄色葡萄球菌免疫显性抗原 A 中，鼠源 IgG 抗体与人类 IgG 抗体的表位识别差异。
Sci Rep. 2017 Aug 15;7(1):8141. doi: 10.1038/s41598-017-08182-9.
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