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一名唐氏综合征患儿及其兄弟姐妹的实验性牙龈炎

Experimental gingivitis in a Down's syndrome child and sibling.

作者信息

Reuland-Bosma W, van Dijk J, Rozeboom T, Poppema S

出版信息

J Clin Microbiol. 1987 May;25(5):949-51. doi: 10.1128/jcm.25.5.949-951.1987.

DOI:10.1128/jcm.25.5.949-951.1987
PMID:2953756
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC266130/
Abstract

Biopsies were taken from a child with Down's syndrome and her sibling under experimental gingivitis conditions and analyzed with monoclonal antibodies. At first, plaque caused a shift from a predominance of T cells to a predominance of B cells. Later, a gradual increase of T cells and a looser arrangement of B cells were observed.

摘要

在实验性牙龈炎条件下，从一名唐氏综合征患儿及其兄弟姐妹身上获取活检样本，并用单克隆抗体进行分析。起初，菌斑导致T细胞优势向B细胞优势转变。后来，观察到T细胞逐渐增加，B细胞排列更松散。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4637/266130/a2c6987bd162/jcm00089-0214-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4637/266130/a2c6987bd162/jcm00089-0214-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4637/266130/a2c6987bd162/jcm00089-0214-a.jpg

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本文引用的文献

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PERIODONTAL DISEASE IN PREGNANCY. II. CORRELATION BETWEEN ORAL HYGIENE AND PERIODONTAL CONDTION.妊娠期牙周病。II. 口腔卫生与牙周状况的相关性
Acta Odontol Scand. 1964 Feb;22:121-35. doi: 10.3109/00016356408993968.
2
PERIODONTAL DISEASE IN PREGNANCY. I. PREVALENCE AND SEVERITY.妊娠期牙周病。I. 患病率与严重程度。
Acta Odontol Scand. 1963 Dec;21:533-51. doi: 10.3109/00016356309011240.
3
T lymphocyte subsets in the inflamed gingiva of human adult periodontitis.成年人类牙周炎炎症牙龈中的T淋巴细胞亚群
J Periodontal Res. 1984 Nov;19(6):595-8. doi: 10.1111/j.1600-0765.1984.tb01322.x.
4
Characterization of the immunocompetent cells in human advanced periodontitis.人类晚期牙周炎中免疫活性细胞的特征分析
J Periodontal Res. 1982 Sep;17(5):472-3. doi: 10.1111/j.1600-0765.1982.tb02030.x.
5
The identification of lymphoid cell subpopulations in sections of human lymphoid tissue and gingivitis in children using monoclonal antibodies.利用单克隆抗体对人淋巴组织切片中的淋巴细胞亚群及儿童牙龈炎进行鉴定。
J Periodontal Res. 1982 May;17(3):247-56. doi: 10.1111/j.1600-0765.1982.tb01151.x.
6
Gingival health and frequency of tooth brushing in the beagle dog model. Clinical findings.比格犬模型中牙龈健康状况与刷牙频率。临床研究结果。
J Clin Periodontol. 1986 Feb;13(2):164-8. doi: 10.1111/j.1600-051x.1986.tb01451.x.
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Scand J Dent Res. 1975 Nov;83(6):314-26. doi: 10.1111/j.1600-0722.1975.tb00444.x.
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Development of gingivitis in pre-school children and young adults. A comparative experimental study.学龄前儿童和年轻人牙龈炎的发展。一项对比性实验研究。
J Clin Periodontol. 1978 Feb;5(1):24-34. doi: 10.1111/j.1600-051x.1978.tb01903.x.
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J Periodontol. 1977 Nov;48(11):705-10. doi: 10.1902/jop.1977.48.11.705.
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